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3-(2-Pyrrolidinyl)pyridine

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3-(2-Pyrrolidinyl)pyridine Basic information
3-(2-Pyrrolidinyl)pyridine Chemical Properties
  • Melting point:235-236 °C(Solv: ethanol (64-17-5))
  • Boiling point:107-108°C 2mm
  • Density 1,074 g/cm3
  • refractive index 1.54
  • Flash point:101°C
  • storage temp. 2-8°C
  • solubility H2O: 50 mg/mL
  • pka9.09±0.10(Predicted)
  • form liquid
  • color yellow
  • Specific Gravity1.074
  • Water Solubility Soluble in acetone, chloroform and water (50mg/ml).
  • Merck 14,6712
  • BRN 81968
  • CAS DataBase Reference5746-86-1(CAS DataBase Reference)
Safety Information
MSDS
3-(2-Pyrrolidinyl)pyridine Usage And Synthesis
  • Chemical PropertiesColourless Oil
  • UsesA metabolite of Nicotine ((N412420). Can catalyze aqueous aldol reactions.
  • Uses

    3-(2-Pyrrolidinyl)pyridine is a tobacco alkaloid and the major Nicotine (N412420) metabolite in brain. Nornicotine appears to activate different nAChR subtypes, has a better pharmacokinetic profile, and produces less toxicity than Nicotine. Nornicotine shows a significant analgesic activity. Nicotine USP Related Compound F (3-(pyrrolidine-2-yl)pyridine).

  • UsesA metabolite of Nicotine. Can catalyze aqueous aldol reactions
  • Safety ProfilePoison by intraperitoneal route.When heated to decomposition it emits very toxic fumesof NOx and HCl. See also NORNICOTINE
3-(2-Pyrrolidinyl)pyridine(5746-86-1)Related Product Information
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