3-(2-Pyrrolidinyl)pyridine
- Product Name:3-(2-Pyrrolidinyl)pyridine
- CAS:5746-86-1
- MF:C9H12N2
- MW:148.2
- EINECS:637-353-0
- Mol File:5746-86-1.mol
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3-(2-Pyrrolidinyl)pyridine Chemical Properties
- Melting point:235-236 °C(Solv: ethanol (64-17-5))
- Boiling point:107-108°C 2mm
- Density 1,074 g/cm3
- refractive index 1.54
- Flash point:101°C
- storage temp. 2-8°C
- solubility H2O: 50 mg/mL
- pka9.09±0.10(Predicted)
- form liquid
- color yellow
- Specific Gravity1.074
- Water Solubility Soluble in acetone, chloroform and water (50mg/ml).
- Merck 14,6712
- BRN 81968
- CAS DataBase Reference5746-86-1(CAS DataBase Reference)
- Hazard Codes Xn,Xi,T,F
- Risk Statements 20/21/22-36/37/38-39/23/24/25-23/24/25-11
- Safety Statements 26-36/37-45-16-7
- RIDADR 2810
- WGK Germany 3
- RTECS QS6350000
- F 3-10
- HazardClass 6.1
- PackingGroup III
- HS Code 29399990
- ToxicityLDLo ipr-rat: 6 mg/kg AJEBAK 25,83,47
- Language:EnglishProvider:SigmaAldrich
- Language:EnglishProvider:ALFA
3-(2-Pyrrolidinyl)pyridine Usage And Synthesis
- Chemical PropertiesColourless Oil
- UsesA metabolite of Nicotine ((N412420). Can catalyze aqueous aldol reactions.
- Uses
3-(2-Pyrrolidinyl)pyridine is a tobacco alkaloid and the major Nicotine (N412420) metabolite in brain. Nornicotine appears to activate different nAChR subtypes, has a better pharmacokinetic profile, and produces less toxicity than Nicotine. Nornicotine shows a significant analgesic activity. Nicotine USP Related Compound F (3-(pyrrolidine-2-yl)pyridine).
- UsesA metabolite of Nicotine. Can catalyze aqueous aldol reactions
- Safety ProfilePoison by intraperitoneal route.When heated to decomposition it emits very toxic fumesof NOx and HCl. See also NORNICOTINE
- Nicotine (+/-)-COTININE-D3 (-)-COTININE NICOTINE, L-, [N-METHYL-3H] (+/-)-NICOTINE-D3 SALICYLATE SALT (+/-)-NICOTINE-METHYL-D3 (+)-NICOTINE (+)-DI-P-TOLUOYLTARTRATE SALT 3-(N-METHYL-2-PYRROLIDINYL)PYRIDINE SULFATE NICOTINE, D [N-METHYL 14C] NICOTINE SALICYLATE rac trans-4-Cotininecarboxylic Acid 3-(2-Pyrrolidinyl)pyridine Pyridine Polyvinylpyrrolidone Pyrrolidine Povidone iodine 1-Methyl-2-pyrrolidinone N-Vinyl-2-pyrrolidone
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