It is used as Wittig-Horner reagent for preparing (Z)-Boc-protected dehydroamino acid derivatives and saturated, unnatural amino acids by subsequent asymmetric hydrogenation.
(+/-)-Boc-a-phosphonoglycine trimethyl ester is used as a Wittig-Horner reagent for preparing (Z)-Boc-protected dehydroamino acid derivatives.
reaction type: Boc solid-phase peptide synthesis
(+/-)-Boc-a-phosphonoglycine trimethyl ester is purified by recrystallization from diethyl ether/pentane (1:1) at 0 °C.
(+/-)-Boc-a-phosphonoglycine trimethyl ester is a reagent should be used in a fume hood.
