Kisspeptin 10 (rat)

Kisspeptin-10 is a neuropeptide and corresponds to amino acids 110-119 of rodent kisspeptin-1 (KiSS1), a metastasis suppressor gene product.

Kisspeptin-10 (mouse, rat) is a potent vasoconstrictor and inhibitor of angiogenesis. Kisspeptin-10 (mouse, rat) is a ligand for the rodent kisspeptin receptor (KISS1, GPR54). Kisspeptin-10 reduces Methotrexate-induced reproductive toxicity as a potential antioxidant compound[1].

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[1] Güven M, et al. Ameliorating effect of kisspeptin-10 on methotrexate-induced sperm damages and testicular oxidative stress in rats. Andrologia. 2018 Oct;50(8):e13057. DOI:10.1111/and.13057