Nsc121218

(4Z)-Lachnophyllum lactone is a enyne derivative. (4Z)-Lachnophyllum lactone shows growth inhibitory activity against Lemna paucicostata (IC50=104 μM), which is a problematic and invasive weed[1]. (4Z)-Lachnophyllum lactone is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

[1] Queiroz SC, et al. Bioassay-directed isolation and identification of phytotoxic and fungitoxic acetylenes from Conyza canadensis. J Agric Food Chem. 2012 Jun 13;60(23):5893-8. DOI:10.1021/jf3010367