Amino-PEG5-azide is developed as a bifunctional PEG reagent with great solubility in aqueous media. The amino group is reactive with carboxylic acids, activated NHS esters. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
17-Azido-3,6,9,12,15-pentaoxaheptadecan-1-amine is a heterobifunctional polyethyleneglycol (PEG) derivative used in the preparation terminal labeling agents of DNA; a useful reagent used in the construction of intramolecular linkers.
reaction type: click chemistry
reagent type: linker
