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GW0742

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GW0742 Basic information
GW0742 Chemical Properties
  • Melting point:134.5-135.5 °C
  • Boiling point:591.5±60.0 °C(Predicted)
  • Density 1.46±0.1 g/cm3(Predicted)
  • storage temp. 2-8°C
  • solubility DMSO: >5 mg/mL
  • pka3.17±0.10(Predicted)
  • form solid
  • color white
  • InChIKeyHWVNEWGKWRGSRK-UHFFFAOYSA-N
Safety Information
  • WGK Germany 3
MSDS
GW0742 Usage And Synthesis
  • Chemical PropertiesLight Yellow Solid
  • UsesA small molecule agonist of the human Peroxisome Proliferator-Activated Recept d (PPAR d). It shows an EC50 of 1.1 nM against PPAR d with 100-fold selectivity over the other human subtypes
  • UsesA small molecule agonist of the human Peroxisome Proliferator-Activated Recept δ (PPAR δ). It shows an EC50 of 1.1 nM against PPAR δ with 100-fold selectivity over the other human subtypes.
  • Biological ActivityPotent and highly selective PPAR δ agonist. EC 50 values are 0.001, 1.1 and 2 μ M for transactivation of human PPAR δ , - α , and - γ receptors respectively. Neuroprotective in rat cerebellar granule neuronal cultures after brief (12-hour) exposure but exhibits inherent toxicity after prolonged (48-hour) incubation. Increases rate of fatty acid oxidation and protects against ischemia/reperfusion injury in neonatal and adult cardiomyocytes.
GW0742(317318-84-6)Related Product Information
GW0742SupplierMore
  • Company Name:Wuhan Deme Biological Technology Co., Ltd Gold
  • Tel:17192727886 171-9272-7886
  • Email:3242502040@qq.com;2305665841@qq.com;
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  • Company Name:J & K SCIENTIFIC LTD.
  • Tel:400-666-7788 010-82848833-
  • Email:jkinfo@jkchemical.com;market6@jkchemical.com
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  • Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
  • Tel:18930552037 821-50328103-801
  • Email:3bsc@sina.com
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  • Company Name:Chemsky(shanghai)International Co.,Ltd.
  • Tel:021-50135380
  • Email:shchemsky@163.com
  •  
  • Company Name:Chemsky(shanghai)International Co.,Ltd.
  • Tel:021-50135380
  • Email:shchemsky@sina.com
  •