基本属性 生物活性靶点体外研究体内研究 用途与合成方法 立福康唑 价格(试剂级) 上下游产品信息 供应商 供应信息 相关产品

立福康唑

立福康唑

中文名称:立福康唑
英文名称:Ravuconazole
CAS号:182760-06-1
分子式:C22H17F2N5OS
分子量:437.47
EINECS号:
Mol文件:182760-06-1.mol
立福康唑 结构式

立福康唑 性质

熔点 64-66°C
比旋光度 D24 -29.1° (c = 1.03 in methanol)
沸点 674.9±65.0 °C(Predicted)
密度 1.38±0.1 g/cm3(Predicted)
储存条件 -20°C Freezer
溶解度 DMF:25mg/mL; DMF:PBS (pH 7.2) (1:4):0.25 mg/mL; DMSO:20mg/mL;乙醇:5mg/mL
形态 结晶固体
酸度系数(pKa) 11.62±0.29(Predicted)
颜色 米白色至黄色
旋光性 (optical activity) [α]/D -27 to -33°, c =1 in methanol

立福康唑 用途与合成方法

Ravuconazole (BMS-207147;ER-30346) 是一种口服的三唑抗真菌药物,能够有效广谱的抑制真菌。

Fungal

Ravuconazole shows a broad spectrum of activity against a wide range of fungi covering Candida spp. , Trichosporon beigelii , C. neoformans and A. fumigatus . The MIC 90 ranges from 0.025 to 0.39 mg/mL.Ravuconazoleshows relatively higher levels of activity against three strains of Candida krusei , with MICs ranging from 0.05 to 0.39 mg/mL.Ravuconazoleshows good activity against T. mentagrophytes , T. rubrum , M. gypseum and M. canis with MICs ranging from 0.05 to 0.39 mg/mL. Ravuconazoleis about two- to four fold more potent than itraconazole and about 40-fold more active than fluconazole against yeasts. Ravuconazoleand itraconazoleare inhibitory to most aspergilli, and against half of the isolates, the activity iscidal. Ravuconazoleand itraconazoleare active, though not cidal, against most hyaline Hyphomycetes , dermatophytes, and the dematiaceous fungi and inactive against Sporothrix schenckii and zygomycetes.

The maximum concentration of ravuconazole in plasma and the area under the concentration-time curve for ravuconazoleshow good linearity over a range of doses from 2 to 40 mg/kg of body weight. Ravuconazole at a dose of 2.5 mg/kg delays mortality significantly compared with the control treatment.Ravuconazole also shows a substantial therapeutic effect against systemic cryptococcosis. Ravuconazole reduces the numbers of CFU in the lungs significantly compared with the numbers of CFU in the lungs of the controls. In an experimental model of oral candidiasis in rats, ravuconazole reduces the numbers of CFU in oral swabs significantly compared with the numbers of CFU in oral swabs from the controls and is more effective than itraconazole and as effective as fluconazole..

立福康唑 价格(试剂级)

更新日期 产品编号 产品名称 CAS号 包装 价格
2024-11-08 HY-14272 立福康唑 182760-06-1 2 mg 400
2024-11-08 HY-14272 立福康唑 182760-06-1 5 mg 600

立福康唑 上下游产品信息

立福康唑供应商 更多

上海裕英生物医药科技有限公司
黄金产品
联系电话:021-50158063
产品介绍:
中文名称:里氟康唑
英文名称:Ravuconazole(Bms 207147; Er30346)
CAS:182760-06-1
纯度:99%
包装信息:1kg,25kg
备注:原料药API
南通诺泰生物医药技术有限公司
黄金产品 大货 现货
联系电话:0513-82206272 17706270880
产品介绍:
CAS:182760-06-1
包装信息:1KG;5KG;25KG
库存量:>1kg
现货日期:2025/1/21 9:08:30
欧利希(上海)医药科技有限公司
黄金产品 现货
联系电话: 17316404525
产品介绍:
中文名称:立福康唑
英文名称:Ravuconazole
CAS:182760-06-1
纯度:98% HPLC
包装信息:5mg,500mg,1g,100g
备注:欧利希试剂,自有研发团队,产品丰富,图谱齐全,诚信经营,质量保障,质量问题无条件退换,确保您购物无忧!欢迎下单咨询!
库存量:500mg
现货日期:2025/1/14 9:39:17
武汉鼎信通药业有限公司
现货
联系电话:027-59207796 13429867250
产品介绍:
中文名称:立福康唑
英文名称:Ravuconazole
CAS:182760-06-1
纯度:99%+
包装信息:5G;10G;100G
备注:5G 10G 50G 100G 200G 500G 1KG 5KG 武汉鼎信通大量现货供应 纯度:99%+ 优势现货 下单当天可发货 订购请致电咨询董浩 13429867250 QQ 3146738450 长期稳定供应
库存量:2000g
现货日期:2025/1/26 19:18:37
武汉鼎信通药业有限公司
现货
联系电话:027-027-83984790 17720532645
产品介绍:
中文名称:立福康唑/雷夫康唑/立福康唑/BMS 207147; ER 30346; Ravuconazole
英文名称:BMS 207147; ER 30346; Ravuconazole
CAS:182760-06-1
纯度:99% HPLC
包装信息:10G;100G;1kg;5kg;25kg
备注:现货直发 品质保障 详情咨询17720532645唐唯(微信同号) QQ: 3489493864 下单前咨询客服获取报价和库存信息,现货用于外贸出口、科学研究和化学试剂等领域!声明:本公司供应的产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或者动物的临床诊断
库存量:200g
现货日期:2025/1/15 8:59:21

立福康唑生产厂家及价格列表

立福康唑 182760-06-1
湖北威德利化学试剂有限公司 2025-01-27

"立福康唑"相关产品信息