Basic information Description Pharmacodynamics Biological activity Interactions Overview Chemical properties Mechanism of action Adverse effects References Safety Related Supplier
Eplerenone Structure

Eplerenone

Chemical Properties

Melting point 241-243°C
alpha  D +5° (c = 0.437 in chloroform)
Boiling point 597.9±50.0 °C(Predicted)
Density  1.31±0.1 g/cm3(Predicted)
storage temp.  Store at RT
solubility  DMSO: soluble2mg/mL, clear (warmed)
form  powder
color  white to beige
λmax 240nm(lit.)
Merck  14,3625
InChIKey UZZAHAKTLYRDOK-MGIDJNSKSA-N
SMILES [C@@]123[C@@]4(C)CCC(=O)C=C4C[C@@H](C(OC)=O)[C@@]1([H])[C@]1([H])CC[C@]4(CCC(=O)O4)[C@]1(C[C@@]2([H])O3)C |&1:0,1,10,15,17,21,27,29,r|
Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It can be used individually or in combination with other medications to treat hypertension by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.

Safety Information

RIDADR  3077
WGK Germany  3
HS Code  29322090
Hazardous Substances Data 107724-20-9(Hazardous Substances Data)

Usage And Synthesis

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