The general method is as follows: The synthesis of 3-nitrobenzamide is based on the synthesis of 4-nitrophenol described below. Add 1 mmol of 69% nitric acid (1 mmol) and 1 mmol of the transition metal complex ([Co(NH3)5Cl]Cl2) to a dichloromethane solution of phenol (1 mmol). Stir the reaction mixture at room temperature for 2 hours. Monitor the reaction progress by TLC. After the reaction is indicated by TLC completion, treat the reaction mixture with sodium carbonate solution. Extract the reaction mixture with dichloromethane. Separate the organic layer, dry with sodium sulfate, and evaporate to obtain the crude product. Purify the crude product on silica gel to obtain 4-nitrophenol as the product. 3-Nitrobenzamide, yield 82%.
