NPPB is a chloride channel blocker and acts as a GPR35 agonist. It maintains protonophoric activity and has been used to uncouple mitochondrial ATP synthesis in phagocytes.
Biochemical probe primarily as a Cl- channel blocker.
ChEBI: 5-Nitro-2-(3-phenylpropylamino)benzoic acid is a nitrobenzoic acid.
Very potent chloride channel blocker.
Potent chloride channel blocker.