Basic information Safety Related Supplier
ChemicalBook >  Product Catalog >  Biochemical Engineering >  Plant extracts >  DIGITONIN

DIGITONIN

Basic information Safety Related Supplier
DIGITONIN Basic information
DIGITONIN Chemical Properties
  • Melting point:230-240 °C (dec.)(lit.)
  • alpha D20 -54° (0.45 g in 15.8 ml methanol)
  • Boiling point:788.4°C (rough estimate)
  • Density 1.1421 (rough estimate)
  • refractive index -52 ° (C=1, EtOH)
  • storage temp. Store at RT.
  • solubility H2O: 10 mg/mL at 95 °C hot, clear, colorless
  • pka12.68±0.70(Predicted)
  • form White powder
  • color white
  • optical activity[α]20/D 54°, c = 2.8 in methanol(lit.)
  • Merck 14,3161
  • BRN 78654
  • InChIKeyFAAZZWIYYDUONB-JYIJKGCVSA-N
  • EPA Substance Registry SystemDigitonin (11024-24-1)
Safety Information
  • Hazard Codes T
  • Risk Statements 23/24/25
  • Safety Statements 22-28-36/37-45
  • RIDADR UN 3462 6.1/PG 3
  • WGK Germany 3
  • RTECS IH2050050
  • 3-10
  • HazardClass 6.1(a)
  • PackingGroup II
  • HS Code 29389090
MSDS
DIGITONIN Usage And Synthesis
  • Chemical Propertieswhite crystalline powder
  • Usesenhances membrane permeability
  • UsesNatural surfactant useful for receptor solubilization and cell permeabilization, e.g., blood platelets, hepatocytes, yeast or tumor cells
  • UsesClinical reagent (cholesterol determination).
  • General DescriptionCrystals or white powder.
  • Air & Water ReactionsForms soapy aqueous suspension .
  • Reactivity ProfileDIGITONIN is incompatible with strong oxidizing agents and strong acids. (NTP, 1992
  • Fire HazardFlash point data for DIGITONIN are not available; however, DIGITONIN is probably combustible.
  • Safety ProfilePoison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. Mutation data reported. See also DIGITALIS. When heated to decomposition it emits acrid smoke and irritating fumes.
  • Purification MethodsThis digitoxin hexa-glycoside can be recrystallised from aqueous 85% EtOH or MeOH/diethyl ether. It is purified by preparative paper chromatography and developed with the upper phase of a mixture of nBuOH/H2O/AcOH (4:5:1), and the spot (RF 0.36) is eluted with 25% CCl3CO2H in CHCl3. It has also been purified by countercurrent distribution. It forms an ethanolate, and complexes with cholesterol and other sterols. [Ruhenstroth-Bauer & Breitenfeld Hoppe Seyler's Z Physiol Chem 302 111 1955, Grisvold J Am Pharm Assoc 23 664 1934, Beilstein 19 IV 1243.]
DIGITONIN(11024-24-1)Related Product Information
DIGITONINSupplierMore
  • Company Name:Infinity SCI Gold
  • Tel:400-106-2016
  • Email:sales@infsci.com
  •  
  • Company Name:Meryer (Shanghai) Chemical Technology Co., Ltd. Gold
  • Tel:400-660-8290 21-61259100-
  • Email:sh@meryer.com
  •  
  • Company Name:Nanjing Spcscientific Technology Co., Ltd. Gold
  • Tel:18994006456
  • Email:sales1@spcscientific.com
  •  
  • Company Name:J & K SCIENTIFIC LTD.
  • Tel:400-666-7788 010-82848833-
  • Email:jkinfo@jkchemical.com;market6@jkchemical.com
  •  
  • Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
  • Tel:18930552037 821-50328103-801
  • Email:3bsc@sina.com
  •