ChemicalBook Product Catalog Biochemical Engineering Nucleoside drugs Nucleotides and their analogs CpG2007

CpG2007

Chemical Properties

form	Solid
color	White to off-white
Sequence	DNA, d(P-thio)(T-C-G-T-C-G-T-T-G-T-C-G-T-T-T-T-G-T-C-G-T-T)

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Animal Model:	Zebrafish infected with Vibrio traumaticus FJ03-X2^[2]
Dosage:	1 μg
Administration:	Intraperitoneal injection; once
Result:	Showed a cumulative mortality rate of 15.0% in treated group while the control group reached 42.1%. Showed a significant decrease in the expression levels of all intestinal immune-related genes such as TNF、IFNg1-2、IL-1β、IL-10, especially IL-1β decreased by 99.88%.