Norisoboldine (10~40 mg/kg; p.o.; 20 days) significantly reduces the severity of joint swelling and erythema during the course of the experiment[1].
Norisoboldine (40 mg/kg; i.g.; 10 days) induces enhancement of CYP1A1 expression and suppresses expressions of Glut1 and HK2 in colons[2].
| Animal Model: | Male ICR mice (18–22 g) |
| Dosage: | 10~40 mg/kg |
| Administration: | P.o. |
| Result: | Significantly reduced the severity of joint swelling and erythema during the course of the experiment.
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| Animal Model: | Female C57BL/6 mice (18–22 g) |
| Dosage: | 40 mg/kg |
| Administration: | I.g. |
| Result: | Induced enhancement of CYP1A1 expression and suppressed expressions of Glut1 and HK2 in colons.
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