4-Nitrophenylboronic acid

4-Nitrobenzeneboronic acid is an arylboronic acid building block that has been used in the synthesis of phenols.

White to brown powder or crystal

Reagent used for

• Ligand-free palladium-catalyzed Suzuki-Miyaura cross-couplings
• Ruthenium catalyzed direct arylation of benzylic sp³ carbons of acyclic amines
• Diels-Alder or C-H activation reactions
• Regioselective Suzuki-Miyaura coupling and tandem palladium-catalyzed intramolecular aminocarbonylation and annulations
• N-arylation of phenylurea using copper acetylacetonate catalyst
• Environmentally benign one-pot synthesis through a double arylation process
• Copper-mediated cyanations
• copper-catalyzed arylations
• Regioselective glycosylations
• Suzuki couplings followed by arylations
• X-ray absorption on rhodium-grafted hydrotalcite catalyst for heterogeneous 1,4-addition reaction of organoboron reagents to electron deficient olefins

Reagent used in Preparation of

• Combretastatin analogs as potential antitumor agents
• Human immunodeficiency virus (HIV) protease inhibitors with antiviral activities against drug-resistant viruses

suzuki reaction

4-Nitrophenylboronic Acid is a useful synthetic intermediate. It is a reagent used for ligand-free palladium-catalyzed Suzuki-Miyaura cross-couplings, Ruthenium catalyzed direct arylation of benzylic sp3 carbons of acyclic amines and Diels-Alder or C-H activation reactions.