Calcium dihydrogen di-L-aspartate is odourless, hygroscopic, soluble in water, and insoluble in organic solvents, with a high absorption rate. The aqueous solution of Calcium dihydrogen di-L-aspartate becomes clear after being light white, with unclear toxic and side effects and good structural stability. Calcium dihydrogen di-L-aspartate raw material is a new generation of nutritional supplement made by nano crushing and molecular chelation of aspartic acid and calcium, which can be regarded as the fourth generation of calcium supplement products. It has multiple effects of calcium supplements and anti-fatigue.