HA-1004 is an inhibitor of PKA, cGKI, PKC, MYLK, and calcium channel protein.
Definition
ChEBI: 2-[2-(5-isoquinolinylsulfonylamino)ethyl]guanidine is a member of isoquinolines.
in vivo
HA-1004 (40 nmol/day; infused by minipumps and delivered at 1 μL/h), it acts simultaneously with morphine to antagonize the phosphorylation of ERK1/2 and TH and inhibit the increase of NA conversion during morphine withdrawal in rats[1].
HA-1004 HYDROCHLORIDE WEAK PROTEIN KINAS E I Supplier
