General procedure: 2,4-difluoro-5-nitrophenol (1.01 g, 5.77 mmol) was suspended in ethyl acetate (EtOAc) and palladium hydroxide (0.08 g, 0.57 mmol) was added. The resulting slurry was stirred and reacted under hydrogen atmosphere for 6 hours. After completion of the reaction, the mixture was filtered through diatomaceous earth (Celite) and the filter cake was washed with ethyl acetate (2 x 10 mL). The filtrates were combined and concentrated to afford 5-amino-2,4-difluorophenol (0.8 g, 96% yield) as a solid product. The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ 9.28 (s, 1H), 6.91 (t, J = 7.2 Hz, 1H), 6.35 (t, J = 8.8 Hz, 1H), 4.84 (br s, 2H); mass spectra (ESI) m/z: 146.0 ([M + H]+).
