solution of 2,3-difluorophenol (103.3 g, 793.9 mmol) in 2-butanone (770 ml) was added to potassium carbonate (128 g, 923 mmol). While stirring, a solution of iodoethane (180 g, 1154 mmol) in 2-butanone (350 ml) was added, and the mixture was stirred under reflux for 3 hours to suspend it. At room temperature, water (200 ml) and toluene (100 ml) were added to the reaction mixture. The separated organic phase was washed with 2N sodium hydroxide (100 ml) and brine (100 ml), respectively. The combined organic layers were dried with anhydrous magnesium sulfate, and the organic solvent was removed by vacuum evaporation. Finally, the residue was purified by vacuum distillation to obtain 2,3-DIFLUOROETHOXYBENZENE.
Synthetic route of 2,3-DIFLUOROETHOXYBENZENE
