m-PEG3-succinimidyl carbonate is a PEG linker containing a succinimidyl carbonate end group. The succinimidyl is amine reactive, forming stable amide bonds. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.
Uses
m-PEG3-succinimidyl carbonate is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] Miller MA, et al. Amphiphilic conjugates of human brain natriuretic peptide designed for oral delivery: in vitro activity screening. Bioconjug Chem. 2006 Mar-Apr;17(2):267-74. DOI:10.1021/bc0501000
