环丙基-1,1-二甲酸单乙酯
环丙基-1,1-二甲酸单乙酯 性质
| 沸点 | 66-69℃ (0.15 Torr) |
|---|---|
| 密度 | 1.339±0.06 g/cm3(Predicted) |
| 储存条件 | Sealed in dry,Room Temperature |
| 酸度系数(pKa) | 3.46±0.20(Predicted) |
| 形态 | 液体 |
| 颜色 | 透明、无色 |
环丙基-1,1-二甲酸单乙酯 用途与合成方法
1559-02-0
3697-66-3
1-(Ethoxycarbonyl)cyclopropanecarboxylic acid was synthesized as follows: A solution of diethyl 1,1-cyclopropanedicarboxylate (20 g) in 1N NaOH (107 mL) and ethanol (220 mL) was hydrolyzed for 16 hours. Ethanol was removed by减压蒸馏. The remaining starting material was extracted with ethyl acetate. The aqueous layer was acidified with 1N HCl. The reaction mixture was then extracted with ethyl acetate and concentrated under reduced pressure. The residue was purified by silica gel column chromatography to afford 1-(ethoxycarbonyl)cyclopropanecarboxylic acid in 94% yield. 1H NMR (CDCl3) δ 1.06 (t, 3H), 1.53 (m, 2H), 1.62 (m, 2H), 4.21 (q, 2H). ESI-MS: m/z 159 [M+H]+ for C7H10O4.
参考文献：
[1] Patent: WO2005/79812, 2005, A1. Location in patent: Page/Page column 45-46
[2] Patent: CN105111155, 2018, B. Location in patent: Paragraph 0038; 0051; 0055; 0056
[3] Patent: US2008/45556, 2008, A1. Location in patent: Page/Page column 21
[4] Patent: US2010/239576, 2010, A1
环丙基-1,1-二甲酸单乙酯 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026-09-15 | XW02369766305 | 1-(乙氧羰基)环丙烷羧酸 | 3697-66-3 | 25G | 564 |
| 2026-09-15 | XW02369766304 | 1-(乙氧羰基)环丙烷羧酸 | 3697-66-3 | 10G | 317 |
