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FUMONISIN B1

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FUMONISIN B1 Basic information
FUMONISIN B1 Chemical Properties
  • Boiling point:713.81°C (rough estimate)
  • Density 1.2207 (rough estimate)
  • refractive index 1.6630 (estimate)
  • Flash point:6 °C
  • storage temp. 2-8°C
  • pka3?+-.0.23(Predicted)
  • form Powder
  • color White to tan
  • CAS DataBase Reference116355-83-0
Safety Information
  • Hazard Codes Xn,T,F
  • Risk Statements 40-36-20/21/22-11
  • Safety Statements 36/37-16-26-45
  • RIDADR 3172
  • WGK Germany 3
  • RTECS TZ8350000
  • HazardClass 6.1(b)
  • PackingGroup III
  • HS Code 29221990
MSDS
FUMONISIN B1 Usage And Synthesis
  • Chemical Propertieswhite to tan powder
  • UsesA mycotoxin produced by mold associated with corn. Fungal metabolite believed to cause leukoencephalomalacia in horses.
  • UsesFumonisin B1 is a major analogue of a family of potent mycotoxins produced by various Fusarium species, associated with animal toxicity worldwide. In vitro, fumonisin B1 inhibits sphingosine N-acyl-transferase (ceramide synthase) and blocks the growth of axons.
  • UsesA serine/threonine phosphatase inhibitor.
  • Biological ActivityMycotoxin produced by Fusarium moniliforme . Potently inhibits sphingosine N-acyltransferase (ceramide synthase), causing an accumulation of sphingoid bases (IC 50 ~ 75 nM). Also inhibits protein phosphatases; IC 50 values are 80, 300, 400, 500 and 3000 μ M for PP5, PP2C α , PP2A, PP1 γ 2 and PP2B respectively.
FUMONISIN B1(116355-83-0)Related Product Information
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