GENERAL STEPS: All reactions were carried out in a 50 mL two-necked round-bottomed flask equipped with a water condenser and a magnetic stirrer. In a typical experiment, a mixture of zeolite HBEA-25 (Si/Al = 25, 0.11 g), o-xylene (0.60 mL, 5 mmol), 65% nitric acid (0.68 mL, 10 mmol) with acetic anhydride (5.0 mL) was stirred and reacted for 10 h at room temperature. After completion of the reaction, the zeolite was removed by filtration and the filtrate was washed sequentially with NaHCO3 solution (3 x 10 mL) and distilled water (3 x 10 mL). The organic phase was separated, dried with anhydrous sodium sulfate and filtered to give a straw yellow liquid product. The isomer distribution and yield of the product were estimated by gas chromatography internal standard method based on peak area. The crude product was further purified by column chromatography and structural identification was carried out by comparing the analytical data with real samples.
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