2-(2-(2-Aminoethoxy)ethoxy)acetic acid

Amino-PEG2-CH2CO2H is a PEG compound containing an amino group with a terminal carboxylic acid. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

White to off-white crystalline powder

[2-(2-Aminoethoxy)ethoxy]acetic Acid is used in the development of chemically modified peptide nucleic acid (PNA) as a probe for qualitative and quantitative detection of DNA. It is also used in the preparation and studies of the biological activities of kappa agonist CovX-bodies.