PO-TAP-1 (Oxazole Blue Monomer, also known as PO-PRO®-1) is a blue fluorescent carbocyanine monomeric dye. PO-TAP-1 is a cell-impermeant nucleic acid stain that is nonfluorescent in the absence of nucleic acids but exhibits a multiple fluorescence enhancement upon binding to dsDNA.
The bright fluorescence signal and low background make PO-TAP-1 ideal for staining nucleic acids on microarrays, as well as for nuclear and chromosome counterstaining in multicolor fluorescence labeling experiments.
The dye is used to detect and count cells and microorganisms, perform nucleic acid sequencing, amplification, and hybridization, and as a temperature sensor.
