4-(Bromomethyl)pyridine hydrobromide

• 3-(4-pyridylmethyl)-2′,3′-di-O-oleyl-5′-O-(4,4′-dimethoxytriphenylmethyl)uridine
• 3-(4-pyridylmethyl)-3′-O-oleyl-5′-O-(4,4-dimethoxytriphenylmethyl)-thymidine
• 1,4-bis(N-hexyl-4-pyridinium)butadiene diperchlorate

• 2-morpholin-4-yl-7-(pyridin-4-ylmethoxy)-4H-1,3-benzoxazin-4-one
• 8-methyl-2-morpholin-4-yl-7-(pyridin-4-ylmethoxy)-4H-1,3-benzoxazin-4-one
• 2-morpholin-4-yl-8-(pyridin-4-ylmethoxy)-4H-1,3-benzoxazin-4-one

586-95-8

73870-24-3

General procedure for the synthesis of 4-(bromomethyl)pyridine hydrochloride from 4-pyridinemethanol: To a 30 mL chloroform solution of 4-pyridinemethanol (3 g, 27.5 mmol) was added phosphorus pentabromide (5.93 g, 13.7 mmol). The reaction mixture was refluxed for 1 hour. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure and the resulting crude product was recrystallized in ethanol to afford 4-(bromomethyl)pyridine hydrochloride as a white solid (4.05 g, 58.1% yield). Electrospray mass spectrometry (positive ion mode) showed m/e = 173 ([M + H]+).