Basic information Safety Related Supplier

RO 20-1724

Basic information Safety Related Supplier
RO 20-1724 Basic information
RO 20-1724 Chemical Properties
Safety Information
  • Hazard Codes Xi
  • Risk Statements 36/37/38
  • Safety Statements 26-36
  • WGK Germany 3
MSDS
RO 20-1724 Usage And Synthesis
  • UsesRo 20-1724 is a cell-permeable, cAMP-specific phosphodiesterase type IV (PDE4) inhibitor (IC50 = 2 μM). It weakly inhibits PDE3 with a Ki value greater than 25 μM. Ro 20-1724 inhibits the release of cytokines and other inflammatory signals as well as prevents the development of reactive oxygen species. It is often used to study cAMP-related functions in vascular cells.
  • UsesRo 20-1724 Is an inhibitor of phosphodiesterase-4, and also very effective for patients with plaque psoriasis. Selective inhibitor of cAMP-specific phosphodiesterase. Selective PDE4 inhibitor.
  • Biological ActivityWidely used inhibitor of cyclic nucleotide phosphodiesterase, selective for PDE4 (IC 50 = 2.0 μ M). Also available as part of the Phosphodiesterase Inhibitor Tocriset™ .
  • Biochem/physiol ActionsInhibitor of cAMP phosphodiesterase. IC50 33 μM in vascular smooth muscle of the aorta.
RO 20-1724(29925-17-5)Related Product Information
RO 20-1724SupplierMore
  • Company Name:J & K SCIENTIFIC LTD.
  • Tel:400-666-7788 010-82848833-
  • Email:jkinfo@jkchemical.com;market6@jkchemical.com
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  • Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
  • Tel:18930552037 821-50328103-801
  • Email:3bsc@sina.com
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  • Company Name:VDM Biochemicals
  • Tel:0330-2528181
  • Email:sales@vdmbio.com
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  • Company Name:BOC Sciences
  • Tel:16314854226
  • Email:info@bocsci.com
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  • Company Name:Shanghai Meishui Chemical Technology Co., Ltd
  • Tel:021-60549325 18616193163
  • Email:mail@meishuichem.com
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