4-Bromobutyric acid

light brown low melting crystals

4-Bromobutyric acid is used as a bifunctional cross-linker and as a pharmaceutical intermediate. It is also used to synthesize 4-Bromobutyryl chloride.

reagent type: cross-linking reagent

4-Bromobutyric acid may be produced by a reaction of Y-butyrolactone with hydrogen bromide. The hydrogen bromide to be used may be gas or an aqueous Solution thereof. The reaction temperature is usually about 10 to 100°C., and the amount of hydrogen bromide to be used is usually about 1 to 10 moles per mole of Y-butyrolactone.