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2',7'-DICHLOROFLUORESCEIN Basic information
2',7'-DICHLOROFLUORESCEIN Chemical Properties
  • Melting point:280 °C (dec.)(lit.)
  • Boiling point:514.77°C (rough estimate)
  • Density 0.79 g/mL at 20 °C
  • refractive index 1.5300 (estimate)
  • Flash point:12°C (53.6°F)
  • storage temp. room temp
  • solubility alcohol: passes test
  • form crystalline
  • pka4.46(at 25℃)
  • color orange to red-brown, powder
  • PH Range4.0 (colorless) - 6.6 (green)
  • Water Solubility Soluble in ethanol and methanol. Slightly dimethyl sulfoxide. Insoluble in water.
  • λmax509nm
  • BRN 58009
  • Stability:Stable. Incompatible with strong oxidizing agents.
  • Major ApplicationElectroluminescent devices, sol-gel silica films, integrated circuits, photoresists, lithographic printing plates, recording material, LED devices, photoconductors, Solid-state dye laser, lithographic printing plates, inks, Fluorescent pH sensors, emissive probes, chemotherapeutic treatment of disease, phototherapeutic treatment of disease, photodynamic treatment of disease
  • CAS DataBase Reference76-54-0(CAS DataBase Reference)
  • EPA Substance Registry SystemSpiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 2',7'-dichloro-3',6'-dihydroxy- (76-54-0)
Safety Information
  • Hazard Codes Xi,F
  • Risk Statements 36/37/38-36-67-11
  • Safety Statements 26-36-16
  • RIDADR UN 1219 3/PG 2
  • WGK Germany 3
  • RTECS NT8050000
  • TSCA Yes
  • HS Code 3204 19 00
2',7'-DICHLOROFLUORESCEIN Usage And Synthesis
  • Chemical Propertiesred to yellow solid
  • UsesWidely used probe, e.g. for determination of carbohydrates by fluorescence densitometry after TLC and determination of H2O2 by chemiluminescence. Fluorescent additives used in indirect fluorimetric detection in OTC-HPLC.
  • Uses2',7'-Dichlorofluorescein is used as an indicator and as a cellular antioxidant activity. It is also used for the determination of carbohydrates and hydrogen peroxide by fluorescence densitometry and chemiluminescence respectively. It is used as an indicator for argentometry by Fajans method. It is also involved in the cellular antioxidant activity assay. It is utilized as an additive in fluorescence and laser studies.
    A new fluorescent sensor for Cd2+ and its application in living cells imaging. Tetrahedron Lett. 2015, 56 (11), 1322-1327.
    Colorimetric and fluorogenic signaling of fluoride ions by thiophosphinated dichlorofluorescein. Dyes Pigm. 2015, 112, 170-175.
  • Definition2',7'-dichlorofluorescein is a member of 2-benzofurans. It has a role as a fluorochrome. It derives from a fluorescin.
  • Application2',7'-dichlorofluorescein has been used as an oxidation-sensitive fluorescent probe to measure ROS (reactive oxygen species) formation in cells.
  • Biological Activity2',7'-dichlorofluorescein is an oxidation-sensitive fluorescent probe. 2′7′-dichlorofluorescein diacetate is oxidized to 2′7′-dichlorofluorescein in the presence of ROS (reactive oxygen species).
2',7'-DICHLOROFLUORESCEIN(76-54-0)Related Product Information
  • Company Name:Jingjiang Dongni chemical products Co., Ltd Gold
  • Tel:18068357565
  • Company Name:Shanghai Macklin Biochemical Co.,Ltd. Gold
  • Tel:15221275939
  • Company Name:J & K SCIENTIFIC LTD.
  • Tel:400-666-7788 010-82848833-
  • Company Name:Meryer (Shanghai) Chemical Technology Co., Ltd.
  • Tel:400-660-8290 21-61259100-
  • Company Name:INTATRADE GmbH
  • Tel:+49 3493/605464