Methyl 2,5-dichlorobenzoate

2,5-dichlorobenzoic acid methyl ester is a plant growth regulator and fungicide. It is moderately soluble in water and is a volatile substance. It is moderately toxic to fish but little else is known about its toxicity to biodiversity. 2,5-dichlorobenzoic acid methyl ester has a moderate mammalian oral toxicity. Little else is known regarding its toxicity to humans.

Methyl 2,5-Dichlorobenzoate is used as a starting material in the preparations of polyphenylenes.

Methyl 2,5-dichlorobenzoate was used as starting reagent in the synthesis of poly(p-phenylene). It was used in isolation of microorganism degrading methyl benzoate, Burkholderia cepacia and its ability to degrade different methyl aromatic esters.

2,5-Dichlorobenzoic acid methyl ester is commercially synthesised via esterification of 2,5-dichlorobenzoic acid with methanol. The production process begins with the chlorination of benzoic acid to yield 2,5-dichlorobenzoic acid, which is then purified and reacted with methanol in the presence of an acid catalyst such as sulphuric acid or hydrochloric acid. This esterification reaction is typically conducted under reflux conditions to ensure complete conversion to the methyl ester. The resulting product is purified through distillation or recrystallisation.

ChEBI: A methyl ester resulting from the formal condensation of the carboxy group of 2,5-dichlorobenzoic acid with methanol. It as used as a plant growth regulator and fungicide for grafting of grapevines.

Topical. It induces callus formation and protects the grafting site while promoting successful tissue fusion

Plant Growth Regulator; Fungicide