4H-Pyran-4-one was used in the synthesis of probes grafted on the lipid headgroups.
1) from Diethylacetone dioxalate by cyclization to Chelidonic acid (gamma-Pyrone-
2,6-dicarboxylic acid). The acid yields 4H-Pyran-4-one by decarboxylation.
2) by heating of I-Methoxypent-l -en-3-yn-5-
al diethylacetal with Methanol and water,
using Mercuric sulfate or Sulfuric acid
catalyst.
ChEBI: A pyranone that is 4H-pyran substituted by an oxo group at position 4.
Purify -pyrone by vacuum distillation; the distillate crystallises and is hygroscopic. It is non-steam vola
