ICI 63197 is a specific cAMP phosphodiesterase (PDE) inhibitor. It is potent in anatagonizing reserpine-induced hypothermia. potent PDE4 inhibitor.
ChEBI: 2-amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one is a member of triazolopyrimidines.
Flammability and Explosibility
Not classified
Potent phosphodiesterase (PDE) 4 inhibitor (IC 50 = 35 nM for inhibition of [ 3 H]-rolipram binding to rat brain). Antidepressant following systemic administration in vivo .
Phosphodiesterase IV (PDE 4) inhibitor
![2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one Structure](/CAS/GIF/27277-00-5.gif)
![2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one USP/EP/BP pictures](/ProductImageEN/2021-08/Small/fa2d6e1d-5954-4c79-8b16-1afd73d0678a.jpg)
![2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one pictures](/ProductImageEN/2021-08/Small/9133a6ed-2dee-4e98-a2bd-8e769acb8bb8.jpg)
![2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one pictures](https://img.chemicalbook.com/ProductImageEN/2019-12/Small/ab0e0088-0c5b-4b05-97b2-09ee3d6714c3.jpg)