Weighed 6-chloro-pyridin-2-amine (2.58g,20.06mmol), added to N,N-dimethylformamide (25mL) was dissolved, weighed N-bromosuccinimide (3.56g,20.00mmol) was added to the above solution, and the reaction was done at room temperature for 0.5 hours. Water was added, extracted with ethyl acetate, the organic phase was washed with saturated brine, dried with anhydrous sodium sulfate, concentrated, and the crude product was purified by silica gel column chromatography (petroleum ether: ethyl acetate = 5:1) to give the title compound (3.60 g, 86.5% yield).
