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Prostratin, PKC activator

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Prostratin, PKC activator Basic information
Prostratin, PKC activator Chemical Properties
  • Melting point:216-219℃
  • Boiling point:550.5±50.0 °C(Predicted)
  • Density 1.31
  • storage temp. ?20°C
  • solubility Soluble in DMSO at 30mg/ml
  • form white powder
  • pka11.40±0.70(Predicted)
Safety Information
  • WGK Germany 3
Prostratin, PKC activator Usage And Synthesis
  • UsesIt is a protein kinase C activator found in the bark of the mamala tree of Samoa, Homalanthus nutans (Euphorbiaceae). Research indicated that prostratin has potential to be useful in the treatment of HIV as it flushes viral reservoirs in latently infected CD4+ T-cells.
  • UsesActivation of latent reservoirs of HIV-infected cells is a treatment strategy designed to reduce viral load and eliminate the perpetuation of retroviral infection. Prostratin is a non-tumor promoting phorbol ester that potently induces HIV-1 reactivation in latent reservoirs of infected Jurkat-LAT-GFP cells . [Cayman Chemical]
  • DefinitionChEBI: A natural product found in Euphorbia fischeriana.
Prostratin, PKC activator(60857-08-1)Related Product Information
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