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PHORBOL 12-MYRISTATE 13-ACETATE

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PHORBOL 12-MYRISTATE 13-ACETATE Basic information
PHORBOL 12-MYRISTATE 13-ACETATE Chemical Properties
  • Boiling point:571.87°C (rough estimate)
  • Density 1.17±0.1 g/cm3 (20 ºC 760 Torr)
  • refractive index 1.4900 (estimate)
  • storage temp. −20°C
  • solubility DMSO: DMSO solutions can be stored dark at −20?#x00b0;C for at least six months.soluble
  • form Fine Crystalline Powder
  • pka11.19±0.70(Predicted)
  • color Off-white to light yellow
  • Water Solubility Very soluble in methanol, soluble in DMSO, chloroform, ethanol or acetone, ether, ethyl acetate, DMF or acetonitrile. Insoluble in water.
  • Sensitive Light Sensitive
  • BRN 2407201
  • InChIKeyPHEDXBVPIONUQT-RGYGYFBISA-N
  • CAS DataBase Reference16561-29-8(CAS DataBase Reference)
  • EPA Substance Registry System12-O-Tetradecanoylphorbol 13-acetate (16561-29-8)
Safety Information
  • Hazard Codes Xi
  • Risk Statements 38-36/37/38
  • Safety Statements 36/37-26
  • RIDADR 2928
  • WGK Germany 3
  • RTECS QH4377000
  • 8-10
  • HazardClass 6.1(a)
  • PackingGroup II
  • HS Code 29153900
MSDS
PHORBOL 12-MYRISTATE 13-ACETATE Usage And Synthesis
  • Chemical Propertieswhite to off-white solid
  • General DescriptionWhite crystals.
  • Air & Water ReactionsPractically water insoluble.
  • Reactivity ProfilePHORBOL 12-MYRISTATE 13-ACETATE is sensitive to acids and alkalis. .
  • Fire HazardFlash point data for PHORBOL 12-MYRISTATE 13-ACETATE are not available; however, PHORBOL 12-MYRISTATE 13-ACETATE is probably combustible.
  • Biological ActivityExtensively used phorbol ester activator of protein kinase C; tumor promoter. Binds to PKC with a K i value of 2.6 nM as measured by displacement of [ 3 H]phorbol 12,13-dibutyrate binding in rat cortex synaptosomal membranes.
PHORBOL 12-MYRISTATE 13-ACETATE(16561-29-8)Related Product Information
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