Ipratropium may induce various side effects, which should be reported to your doctor if they persist or become severe. These may include dizziness, nausea, heartburn, constipation, dry mouth, difficulty urinating, painful urination, frequent urge to urinate, and back pain. Additionally, some side effects can be serious and require immediate medical attention. These include the development of a rash, hives, itching, swelling of the eyes, face, lips, tongue, throat, hands, feet, ankles, or lower legs, hoarseness, difficulty breathing or swallowing, rapid or irregular heartbeat, and chest pain.