Ecdysterone is considered to be generally safe as long as it’s not overused. In the U.S., it’s currently not banned or treated like a steroid, however it is on the World Anti-Doping Agency (WADA) 2021 Monitoring Program list, which means WADA intends to gather more information about the substance to determine if it should be prohibited or not.
One of the most reliable studies mentioned above found that taking it in supplement form did not lead to symptoms of liver or kidney toxicity. It also seems to lead to fewer side effects compared to other steroid drugs, such as changes in appetite, mood, libido, hair growth and sleep.