Betamethasone Valerate

Product NameBetamethasone Valerate
CAS2152-44-5
MFC27H37FO6
MW476.58
EINECS218-439-3
MOL File2152-44-5.mol

Chemical Properties

Melting point	183-184°
alpha	D +77° (dioxane)
Boiling point	598.9±50.0 °C(Predicted)
Density	1.1174 (estimate)
storage temp.	2-8°C
solubility	Practically insoluble in water, freely soluble in acetone and in methylene chloride, soluble in ethanol (96 per cent).
form	Solid
pka	12.90±0.70(Predicted)
color	White
Merck	13,1183
BRN	4240001
InChIKey	SNHRLVCMMWUAJD-SUYDQAKGSA-N
SMILES	[C@]12(C)C[C@@H]([C@]3(F)[C@@]4(C)C=CC(=O)C=C4CC[C@@]3([H])[C@]1([H])C[C@H](C)[C@@]2(C(=O)CO)OC(=O)CCCC)O \|&1:0,3,4,6,16,18,21,23,r\|
CAS DataBase Reference	2152-44-5(CAS DataBase Reference)
EPA Substance Registry System	.beta.-Methasone 17-valerate (2152-44-5)

Safety Information

Hazard Codes	Xn
Risk Statements	48
Safety Statements	22-24/25
WGK Germany	WGK 2
RTECS	TU3835000
HS Code	2937229000
Storage Class	6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
Hazard Classifications	Repr. 1B STOT RE 2
Toxicity	mouse,LD50,intraperitoneal,632mg/kg (632mg/kg),Shikoku Igaku Zasshi. Shikoku Medical Journal. Vol. 29, Pg. 153, 1973.

MSDS

Provider	Language
1,4-Pregnadiene-11b,17a,21-triol-9a-fluoro-16b-methyl-3,20-dione 17-valerate	English
SigmaAldrich	English

Usage And Synthesis

Description

Betamethasone Valerate is used to help relieve redness, itching, swelling, or other discomfort caused by skin conditions. It is used for scalp problems. This medicine is a corticosteroid (cortisone-like medicine or steroid).

Uses

Betamethasone Valerate is used to treat a variety of skin conditions (such as eczema, dermatitis, allergies, rash). Betamethasone reduces the swelling, itching, and redness that can occur in these types of conditions. This medication is a medium-strength corticosteroid.

Side effects

Stinging, burning, itching, irritation, dryness, or redness of the skin may occur when this medication is first applied to the skin. These effects should disappear in a few days as your body adjusts to the medication.

Tell your doctor right away if you have any serious side effects, including: stretch marks, skin thinning/discoloration, acne, extreme/unwanted hair growth, small red bumps on the skin (folliculitis).

Precautions

Use Betamethasone Valerate on the skin only. However, do not use it on the face, groin, or underarms unless directed to do so by your doctor.

Wash and dry your hands before using. Clean and dry the affected area. Apply a thin film of medication to the affected area and gently rub in, usually 1-3 times daily or as directed by your doctor. Do not bandage, cover, or wrap the area unless directed to do so by your doctor.

After applying the medication, wash your hands unless you are using this medication to treat the hands. When applying this medication near the eyes, avoid getting it in the eyes because this may worsen or cause glaucoma. Also, avoid getting this medication in the nose or mouth. If you get the medication in these areas, rinse with plenty of water.