Dihexadecyl Phosphate

Dihexadecyl phosphate is a negatively-charged synthetic phospholipid that has been used to impart a negative charge to neutral liposomes. It has also been used in the generation of micelles, liposomes, and other types of artificial membranes, including niosomes for drug delivery. Formulations containing dihexadecyl phosphate have been used as emulsifying agents in cosmetics.

Dihexadecyl phosphate is a phospholipid abundantly present in various organisms and extensively employed in diverse laboratory experiments. This highly hydrophobic and lipophilic compound comprises two long-chain fatty acids and a phosphate group. It assumes a pivotal role in upholding cell membrane integrity and ensuring cellular environment stability. In cell culture applications, Dihexadecyl phosphate improves cellular permeability and membrane function. Additionally, it serves as a valuable tool in cell-based assays, facilitating the assessment of cell viability.