Veratric acid is a kind of common chemical synthetic intermediate, being widely used in fields such as industry, medicine, agricultural, is the key intermediate of synthetic drugs alfuzosin hydrochloride compounds such as.
Veratric acid (3,4-Dimethoxybenzoic acid) is an orally active phenolic compound derived from vegetables and fruits, has antioxidant and anti-inflammatory activities. It also acts as a protective agent against hypertension-associated cardiovascular remodelling. Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation.
A method for synthesizing veratric acid: performing disproportionation salification reaction on veratraldehyde with aldehyde and alkali in alcohol/water solvent, and acidifying to obtain veratric acid.
