190 at 298nm in aqueous base at 1mM 409 at 231nm in aqueous base at 1mM 466 at 230nm in aqueous acid at 1mM 68 at 278nm in aqueous acid at 1mM
Merck
14,851
BRN
779271
Exposure limits
ACGIH: TWA 5 mg/m3 NIOSH: TWA 5 mg/m3
BCS Class
3
Stability
Stable. Keep dry. Incompatible with strong oxidizing agents, strong bases, strong acids, various other compounds such as iodides, iron salts, quinine salts, etc.
P270：Do not eat, drink or smoke when using this product.
P301+P312：IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501：Dispose of contents/container to..…
Description
Aspirin is a non-selective, irreversible COX inhibitor. The IC50 values for ovine COX-1 and -2 are 0.75 and 1.25 mM, respectively. Aspirin acetylates COX-1 at Ser530 and COX-2 at Ser516 resulting in irreversible enzyme inhibition.
