Identification Chemical Properties Safety Data Raw materials And Preparation Products Hazard Information Material Safety Data Sheet(MSDS) Questions And Answer Spectrum Detail Well-known Reagent Company Product Information Supplier Related Products


Name Acetylsalicylic acid
CAS 50-78-2
EINECS(EC#) 200-064-1
Molecular Formula C9H8O4
MDL Number MFCD00002430
Molecular Weight 180.16
MOL File 50-78-2.mol

Chemical Properties

Appearance Acetylsalicylic acid is a white crystalline solid with a slightly bitter taste. It is odorless but hydrolyzes in moist air to give an acetic acid odor
Melting point  134-136 °C (lit.)
Boiling point  272.96°C (rough estimate)
density  1.35
refractive index  1.4500 (estimate)
Fp  250 °C
storage temp.  Store at RT.
solubility  H2O: 10 mg/mL at 37 °C
form  crystalline
color  white
pka 3.5(at 25℃)
Stability: Stable. Keep dry. Incompatible with strong oxidizing agents, strong bases, strong acids, various other compounds such as iodides, iron salts, quinine salts, etc.
Water Solubility  3.3 g/L (20 ºC)
Usage Analgesic; antipyretic; anti-inflammatory; antithrombotic
Merck  14,851
BRN  779271
Exposure limits ACGIH: TWA 5 mg/m3
NIOSH: TWA 5 mg/m3
CAS DataBase Reference 50-78-2(CAS DataBase Reference)
NIST Chemistry Reference Benzoic acid, 2-(acetyloxy)-(50-78-2)
EPA Substance Registry System 50-78-2(EPA Substance)

Safety Data

Hazard Codes  Xn
Risk Statements 
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin .
Safety Statements 
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
WGK Germany  1
RTECS  VO0700000
HazardClass  6.1
PackingGroup  III
HS Code  29182200
Safety Profile
Poison by ingestion, intraperitoneal, and possibly other routes. Human systemic effects by ingestion: acute pulmonary edema, body temperature increase, changes in kidney tubules, coma, constipation, dehydration, hematuria, hepatitis, nausea or vomiting, respiratory stimulation, somnolence, tinnitus, decreased urine volume. Implicated in aplastic anemia. A 10 gram dose to an adult may be fatal. A human teratogen. Human reproductive effects by ingestion and possibly other routes: menstrual cycle changes, parturition, various effects on newborn including Apgar score, developmental abnormalities of the cardlovascular and respiratory systems. Experimental animal reproductive effects. Human mutation data reported. An allergen; skin contact, inhalation, or ingestion can cause asthma, sneezing, irritation of eyes and nose, hves, and eczema. Combustible when exposed to heat or flame. When heated to decomposition it emits acrid smoke and fumes.
Hazardous Substances Data 50-78-2(Hazardous Substances Data)
LD50 orally in mice, rats: 1.1, 1.5 g/kg (Hart)

Raw materials And Preparation Products

Hazard Information

Material Safety Data Sheet(MSDS)

Questions And Answer

Well-known Reagent Company Product Information