팜옥사돈

한글명:팜옥사돈

카스 번호131807-57-3

상품명:Famoxadone

CBNumberCB8439206

분자식C22H18N2O4

포뮬러 무게374.39

MOL 파일131807-57-3.mol

동의어(한글)

팜옥사돈

3-(아닐리노)-5-메틸-5-[4-(페녹시)페닐]-1,3-옥사졸리딘-2,4-다이온

3-아닐리노-5-메틸-5-(4-페녹시페닐)-1,3-옥사졸리딘-2,4-다이온

화학적 성질

녹는점	140.3～141.8℃
끓는 점	491.3±55.0 °C(Predicted)
밀도	1.327±0.06 g/cm3(Predicted)
증기압	6.4 x 10^-7 Pa (20 °C)
인화점	2 °C
저장 조건	0-6°C
용해도	DMSO: 100 mg/mL (267.10 mM)
물리적 상태	Solid:particulate/powder
수용성	0.243 mg^-1 (pH 5), 0.011 mg l^-1 (pH 7) at 20 °C
산도 계수 (pKa)	0.63±0.40(Predicted)
색상	White to yellow
LogP	4.65-5.08 at 20℃ and pH4-7
표면장력	73mN/m at 90μg/L and 20.4℃
EPA	Famoxadone (131807-57-3)

위험 및 안전 성명

위험품 표기	Xn,N,F
위험 카페고리 넘버	48/22-50/53-36-20/21/22-11
안전지침서	46-60-61-36-26-16-36/37
유엔번호(UN No.)	UN1648 3/PG 2
WGK 독일	2
유해 물질 데이터	131807-57-3(Hazardous Substances Data)
독성	LD50 in rats (mg/kg): >5000 orally; >2000 dermally (Joshi, Sternberg)

그림문자(GHS)

팜옥사돈 화학적 특성, 용도, 생산

개요
Famoxadone is an oxazolidinedione fungicide. Although famoxadone is not a strobilurin derivative, it shares the same mechanism of action. Famoxadone provides control of a broad spectrum of fungi but is particularly effective against downy mildew (P. viticola), late and early blights (Phytophthora infestans and Alternaria solani), the Septoria complex, and barley net blotch at rates of 50 to 200 g ai/ha. Target crops include vines, potatoes/tomatoes, cereals, sugar beets, canola, and cucumber. It shows good protectant, translaminar and residual control, with excellent rainfastness and good crop safety. As was seen for trifloxystrobin, it is particularly effective against grape downy mildew when applied in mixture with cymoxanil. The cereal disease spectrum and level of disease control are improved when famoxadone is mixed with triazole fungicides such as flusilazole.
화학적 성질
Brown Solid
용도
Famoxadone is a known fungicide used in the protection of agricultural products against various fungal diseases and other biotic stresses such as pests.
농업용
Fungicide: Tanos 50-DF is recommended for use as a preventative fungicide for control of late blight and early blight on potatoes and field tomatoes.
상품명
DPX-JE874®; FAMOXATE®; MEDLEY®; TANOS-50DF®
Pharmacology
Famoxadone inhibits activity of ubiquinol : cytochrome c oxidoreductase at the Qo site of complex III, the same target protein as the strobilurins (34,35). However, studies show a difference in the potency of various strobilurins compared with famoxadone in single amino acid mutants of the cytochrome b protein, suggesting that this compound may interact differently with the target protein (38).
신진 대사 경로
Famoxadone undergoes extensive degradation and metabolism in aqueous and soil environments, in wheat plants, rats, goats and hens via common pathways. The primary reactions include the hydrolytic opening of the oxazolidinedione ring, aryl hydroxylation, cleavage of the phenoxyphenyl and the oxazolidinedione-aminophenyl linkages and conjugation. More than 25 degradation products have been identified.

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