テトラメチルチウラムジスルフィド

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Danger

• 危険有害性情報

  H315：皮膚刺激

  H317：アレルギー性皮膚反応を起こすおそれ

  H319：強い眼刺激

  H340：遺伝性疾患のおそれ

  H361：生殖能または胎児への悪影響のおそれの疑い

  H370：臓器の障害

  H372：長期にわたる、または反復暴露により臓器の障 害

  H410：長期的影響により水生生物に非常に強い毒性

• 注意書き

  P201：使用前に取扱説明書を入手すること。

  P202：全ての安全注意を読み理解するまで取り扱わないこ と。

  P260：粉じん/煙/ガス/ミスト/蒸気/スプレーを吸入しないこ と。

  P264：取扱い後は皮膚をよく洗うこと。

  P264：取扱い後は手や顔をよく洗うこと。

  P270：この製品を使用する時に、飲食または喫煙をしないこ と。

  P271：屋外または換気の良い場所でのみ使用すること。

  P272：汚染された作業衣は作業場から出さないこと。

  P273：環境への放出を避けること。

  P280：保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。

  P302+P352：皮膚に付着した場合：多量の水と石鹸で洗うこと。

  P305+P351+P338：眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。

  P333+P313：皮膚刺激または発疹が生じた場合：医師の診断/手当てを 受けること。

  P337+P313：眼の刺激が続く場合：医師の診断/手当てを受けること。

  P391：漏出物を回収すること。

  P405：施錠して保管すること。

  P501：内容物/容器を．．．に廃棄すること。

テトラメチルチウラムジスルフィド 価格

MSDS Information

• TMTD

テトラメチルチウラムジスルフィド 化学特性,用途語,生産方法

• 外観

  白色～うすい黄色粉末～結晶

• 用途

  殺菌剤, 天然ゴム、合成ゴム用加硫促進剤。

• 効能

  殺真菌薬

• 説明

  Tetramethylthiuram disulfide is a rubber chemieal, an accelerator of vulcanization. It represents the most commonly positive allergen contained in the "thiuram mix". The most frequent occupational categories are the metal industry, homemakers, health services and laboratories, building industries, and shoemakers.

• 化学的特性

  white to almost white powder

• 物理的性質

  Colorless to white to cream-colored crystals. May darken on exposure to air or light.

• 使用

  Tetramethylthiuram disulfide is used as fungicide; bacteriostat; pesticide; rubber vulcanization accelerator; scabicide; seed disinfectant; animal repellent; insecticide; lube-oil additive; wood preservative; in antiseptic sprays; in the blending of lubrieant oils; used against Botrytis, rusts and downy mildews; seed dressing against "damping off' and verticillium wilt; ethanol antagonist and deterrent in mixtures of the methyl, ethyl, propyl, and butyl derivatives; antioxidant in polyolefin plastics; peptizing agent in polysulphide elastomers; in soaps and rodent repellents; nut, fruit, and mushroom disinfectant.

• 定義

  ChEBI: An organic disulfide that results from the formal oxidative dimerisation of N,N-dimethyldithiocarbamic acid. It is widely used as a fungicidal seed treatment.

• 一般的な説明

  A liquid solution of a white crystalline solid. Primary hazard is to the environment. Immediate steps should be taken to limit spread to the environment. Easily penetrates the soil to contaminates groundwater and waterways.

• 空気と水の反応

  Insoluble in water. Decomposes in acidic media to give toxic products. Decomposes to an extent on prolonged exposure to heat, air or moisture.

• 反応プロフィール

  TMTD is incompatible with oxidizing materials and strong acids. Also incompatible with strong alkalis and nitrating agents .

• 危険性

  Toxic by ingestion and inhalation, irritant to skin and eyes. Body weight and hematologic effects. Questionable carcinogen.

• 健康ハザード

  Inhalation of dust may cause respiratory irritation. Liquid irritates eyes and skin and may cause allergic eczema in sensitive individuals. Ingestion causes nausea, vomiting, and diarrhea, all of which may be persistent; paralysis may develop.

• 火災危険

  Special Hazards of Combustion Products: Toxic and irritating oxides of sulfur are formed. Carbon disulfide may be formed from unburned material.

• 作用机制

  菌類の種々の酵素（SH酵素や金属酵素）を阻害することにより，胞子発芽や菌糸成長を阻害する

• 农业用途

  Fungicide, Rodenticide: Thiram is used as a fungicide to prevent crop damage in the field and to prevent crops from deterioration in storage or transport. Thiram is also used as a seed, nut, fruit, and mushroom disinfectant from a variety of fungal diseases. In addition, it is used as an animal repellent to protect fruit trees and ornamentals from damage by rabbits, rodents, and deer. Thiram has been used in the treatment of human scabies, as a sun screen, and as a bactericide applied directly to the skin or incorporated into soap. Thiram is used as a rubber accelerator and vulcanizer and as a bacteriostat for edible oils and fats. It is also used as a rodent repellent, wood preservative, and may be used in the blending of lubricant oils. Registered for use in EU countries. Registered for use in the U.S.

• 接触アレルゲン

  TITD is a rubber vulcanization accelerator

• 安全性プロファイル

  Poison by ingestion and intraperitoneal routes. Questionable carcinogen with experimental tumorigenic and teratogenic data. Other experimental reproductive effects. Mutation data reported, Affects human pulmonary system. A rmld allergen and irritant. Acute poisoning in experimental animals produced liver, hdney, and brain damage. Dangerous in a fire; see NITROGEN MONOXIDE and SULFUR DIOXIDE.

• 職業ばく露

  Thiram is a dithiocarbamate. Some thiurams have been used as rubber components: thiram is used as a rubber accelerator and vulcanizer; a seed, nut, fruit, and mushroom disinfectant; a bacteriostat for edible oils and fats; and as an ingredient in suntan and antiseptic sprays and soaps. It is also used as a fungicide, rodent repellent; wood preservative; and may be used in the blending of lubricant oils.

• 発がん性

  Thiram also was not carcinogenic in rats by gavage or in mice by single subcutaneous injection. In skin painting studies in mice thiram had tumor-initiating and -promoting activity but was not a complete carcinogen.
  Thiram was genotoxic to insects, plants, fungi, and bacteria: it induced sister chromatid exchange and unscheduled DNA synthesis in cultured human cells. Despite established genotoxicity in vitro, it showed no clastogenic and/or aneugenic activity in vivo after oral administration to mice at the maximum tolerated dose.

• 代謝経路

  Dialkyldithiocarbamates chelate copper and inhibit pyruvate dehydrogenase. It is likely that the mode of action of chelators is principally through their effect on lipoamide containing dehydrogenases (Corbett et al., 1984). Thiram generates dimethyldithiocarbamic acid by being cleaved in acidic conditions and in biological media. The acid is conjugated with glucose and alanine in plants and with glucuronic acid in mammals. Dimethyldithiocarbamic acid is further degraded to dimethylamine and CS2. An extensive review of the properties of dithiocarbamate pesticides was published by the World Health Organisation (WHO, 1988) from which much of the following information is taken.

• 輸送方法

  UN2771 Thiocarbamate pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.

• 純化方法

  Crystallise thiram (three times) from boiling CHCl3, then recrystallise it from boiling CHCl3 by adding EtOH dropwise to initiate crystallisation, and allow it to cool. Finally it is precipitated from cold CHCl3 by adding EtOH (which retains the monosulfide in solution). [Ferington & Tobolsky J Am Chem Soc 77 4510 1955, Beilstein 4 IV 242.]

• 不和合性

  Dust may form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine,fluorine, etc.); contact may cause fires or explosions. Keep away from strong alkaline materials, strong acids, strong bases and nitrating agents.

• 廃棄物の処理

  Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal. Thiram can be dissolved in alcohol or other flammable solvent and burned in an incinerator with an afterburner and scrubber.

テトラメチルチウラムジスルフィド 上流と下流の製品情報

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テトラメチルチウラムジスルフィド スペクトルデータ(¹HNMR、¹³CNMR、IR1、IR2、MS、Raman)

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