エチアジド

エチアジド 化学特性,用途語,生産方法

• 効能

  利尿薬

• Originator

  Ethiazide,Tokyo Tanabe,Japan,1970

• Manufacturing Process

  A mixture of 2.9 grams of 5-chloro-2,4-disulfamyl-aniline in 20 ml of anhydrous diethylene glycoldimethylether, 0.44 gram of propionaldehyde and 0.5 ml of a solution of hydrogen chloride in ethyl acetate (109.5 grams hydrogen chloride per 1,000 ml) is heated to 80° to 90°C and maintained at that temperature for 1 hour. The reaction mixture is concentrated under reduced pressure; on addition of water, the product separates and is then recrystallized from ethanol or aqueous ethanol to yield the desired 6-chloro-3- ethyl-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide, MP 269° to 270°C.

• Therapeutic Function

  Diuretic, Cardiotonic, Smooth muscle relaxant, Respiratory stimulant

エチアジド 上流と下流の製品情報

エチアジド 生産企業

Global(8)Suppliers

1824-58-4, エチアジド キーワード