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4-Amino-5-aminomethyl-2-methylpyrimidine

4-Amino-5-aminomethyl-2-methylpyrimidine Structure
4-Amino-5-aminomethyl-2-methylpyrimidine
  • CAS No.95-02-3
  • Chemical Name:4-Amino-5-aminomethyl-2-methylpyrimidine
  • CBNumber:CB9757404
  • Molecular Formula:C6H10N4
  • Formula Weight:138.17
  • MOL File:95-02-3.mol
4-Amino-5-aminomethyl-2-methylpyrimidine Property
  • Melting point 270-272°C
  • Boiling point 121-125 °C
  • Density 1.207
  • vapor pressure 0.012-0.019Pa at 20-25℃
  • storage temp. -20°C Freezer
  • solubility DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly)
  • form Solid
  • pka 7.70±0.29(Predicted)
  • color Off-White to Beige
  • PH 10.65 at 20℃ and 10g/L
  • InChI InChI=1S/C6H10N4/c1-4-9-3-5(2-7)6(8)10-4/h3H,2,7H2,1H3,(H2,8,9,10)
  • InChIKey OZOHTVFCSKFMLL-UHFFFAOYSA-N
  • SMILES C1(C)=NC=C(CN)C(N)=N1
  • LogP -2.27 at 20℃ and pH7
  • Surface tension 72.77mN/m at 1g/L and 20℃
  • FDA UNII EU1UNR0P28
Safety
  • HS Code  :2933599590
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302-H315-H319-H332-H335
  • Precautionary statements P280-P305+P351+P338-P310
4-Amino-5-aminomethyl-2-methylpyrimidine Price More Price(1)
  • Brand: TCI Chemicals (India)
  • Product number: A2633
  • Product name : 4-Amino-5-aminomethyl-2-methylpyrimidine
  • Purity: 
  • Packaging: 200MG
  • Price: ₹20900
  • Updated: 2022/05/26
  • Buy: Buy

4-Amino-5-aminomethyl-2-methylpyrimidine Chemical Properties,Usage,Production

  • Chemical Properties Off-White Solid
  • Uses Substrate for TenA enzyme in the thiamin salvage pathway
  • Definition ChEBI: An aminopyrimidine compound having its amino substituent at the 4-position together with methyl and aminomethyl substituents at the 2- and 5-positions respectively.
  • Synthesis In an autoclave, the mixture of 4-Amino-5-aminomethyl-2-methylpyrimidine (2.0 kg, 15 mol), modified Raney nickel (wet weight 300 g), and saturated methanol solution of ammonia (20 L) was heated to 100 ℃ and stirred for 5 h at this temperature under 4 MPa hydrogen pressure. Then, the mixture was cooled to room temperature and filtered; 4-Amino-5-aminomethyl-2-methyl pyrimidine was obtained as a white solid (2.0 kg, 98%) by concentrating the filtrate[1].
    4-AMINO-5-AMINOMETHYL-2-METHYLPYRIMIDINE, DIHYDROCHLORIDE
  • References [1] Lei Zhao, Fen-Er Chen, Xiao-Dong Ma. “Development of Two Scalable Syntheses of 4-Amino-5-aminomethyl-2-methylpyrimidine: Key Intermediate for Vitamin B1.” Organic Process Research & Development 16 1 (2011): 57–60.
4-Amino-5-aminomethyl-2-methylpyrimidine Preparation Products And Raw materials
Raw materials
Preparation Products
4-Amino-5-aminomethyl-2-methylpyrimidine Suppliers
Global(95)Suppliers
  • Supplier：
    Henan Tianfu Chemical Co.,Ltd.
  • Tel：+86-0371-55170693<br/>+86-19937530512
  • Email：info@tianfuchem.com
  • Country：China
  • ProdList：21628
  • Advantage：55
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    Alchem Pharmtech,Inc.
  • Tel：8485655694
  • Email：sales@alchempharmtech.com
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4-Amino-5-aminomethyl-2-methylpyrimidine Spectrum
95-02-3, 4-Amino-5-aminomethyl-2-methylpyrimidine Related Search:
  • PYRIMIDINE
  • Heterocycle-Pyrimidine series
  • Nucleotides and Nucleosides
  • Heterocycles
  • Enzyme substrates
  • Aromatics
  • Amines
  • Nucleotides
  • Bases & Related Reagents
  • 杂质对照品
  • 高端化学
  • 嘧啶
  • C6H10N42HCl
  • C6H12Cl2N4
  • 硫胺素杂质34
  • 硫胺杂质15
  • 维生素B1杂质9
  • 盐酸硫胺素(维生素B1)杂质19
  • 硫胺素杂质48
  • 硫胺素杂质16
  • 4-氨基-2-甲基-5-(氨甲基)嘧啶/4-AMINO-5-AMINOMETHYL-2-METHYLPYRIMIDINE, DIHYDROCHLORIDE
  • 4-氨基-5-氨甲基-2-甲基嘧啶
  • 4-氨基-2-甲基-5-(氨甲基)嘧啶
  • 4-氨基-5-氨基甲基-2-甲基嘧啶
  • 95-02-3
  • Thiamine Impurity 34
  • Thiamine /Vitamin B1 Impurity 19
  • Vitamin B1 Impurity 9
  • Diazinon Impurity 6 (Diazoxon)
  • 4-AMINO-5-AMINOMETHYL-2-METHYLPYRIMIDINE
  • Thiamine Impurity 48
  • 4-amino-2-methylpyrimidine-5-methylamine
  • Grewe DiaMine
  • 2-methyl-4-amino-5-aminomethylpyrimidine
  • 4-AMINO-5-AMINOMETHYL-2-METHYLPYRIMIDINE, DIHYDROCHLORIDE ISO 9001：2015 REACH
  • Thiamine Impurity 16
  • 2-methyl-4-amino-5-aminomethylpyrimidine 2HCl
  • 4-Amino-5-aminomethyl-2-methylpyrimidine hydrochloride
  • 5-PyriMidineMethanaMine,4-aMino-2-Methyl-
  • 5-(Aminomethyl)-4-amino-2-methylpyrimidine
  • 5-Pyrimidinemethanamine, 4-amino-2-methyl- (9CI)
  • 4-AMINO-5-AMINOMETHYL-2-METHYLPYRIMIDINE, DIHYDROCHLORIDE
  • 4-AMINO-2-METHYL-5-PYRIMIDINEMETHANAMINE, DIHYDROCHLORIDE
  • (4-amino-2-methyl-pyrimidin-5-yl)methylamine
  • 5-Aminomethyl-2-methyl-4-pyrimidineamine
  • 2-Methyl-5-(aminomethyl)-4-pyrimidinamine
  • 2-Methyl-4-aminopyrimidine-5-methanamine
  • 4-Amino-2-methyl-5-pyrimidinemethanamine,dihydrochlorine

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