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BRAZILIN

BRAZILIN Structure
BRAZILIN
  • CAS No.474-07-7
  • Chemical Name:BRAZILIN
  • CBNumber:CB9350126
  • Molecular Formula:C16H14O5
  • Formula Weight:286.28
  • MOL File:474-07-7.mol
BRAZILIN Property
  • Melting point 156-157℃
  • Boiling point 348.65°C (rough estimate)
  • Density 1.1924 (rough estimate)
  • refractive index 1.6200 (estimate)
  • storage temp. 2-8°C
  • solubility DMSO:43.5(Max Conc. mg/mL);151.95(Max Conc. mM)
    DMF:30.0(Max Conc. mg/mL);104.79(Max Conc. mM)
    Ethanol:30.0(Max Conc. mg/mL);104.79(Max Conc. mM)
    PBS (pH 7.2):10.0(Max Conc. mg/mL);34.93(Max Conc. mM)
  • form A crystalline solid
  • Colour Index 75280
  • color Yellow to brown
  • optical activity [α]/D 108.0 to 133.0°, c =0.5 in methanol
  • FDA UNII FZ39SW1K10
  • EPA Substance Registry System Brazilin (474-07-7)
  • UNSPSC Code 41116107
  • NACRES NA.77
Safety
  • Safety Statements  :24/25
  • HS Code  :29329990
  • NFPA 704:
    0
    2 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H315-H319-H335
  • Precautionary statements P261-P264-P271-P280-P302+P352-P305+P351+P338
BRAZILIN Price More Price(5)
  • Brand: Sigma-Aldrich(India)
  • Product number: SML2132
  • Product name : Brazilin
  • Purity: 
  • Packaging: 5MG
  • Price: ₹10955.7
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: SML2132
  • Product name : Brazilin
  • Purity: 
  • Packaging: 25MG
  • Price: ₹44155.8
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: ottokemi
  • Product number:  B 1990
  • Product name : Brazilin
  • Purity: 98%
  • Packaging: 5mg
  • Price: ₹9729
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: ottokemi
  • Product number:  B 1990
  • Product name : Brazilin
  • Purity: 98%
  • Packaging: 100mg
  • Price: ₹10809
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: ottokemi
  • Product number:  B 1990
  • Product name : Brazilin
  • Purity: 98%
  • Packaging: 25mg
  • Price: ₹39069
  • Updated: 2022/05/26
  • Buy: Buy

BRAZILIN Chemical Properties,Usage,Production

  • Description Brazilin is an isoflavonoid originally isolated from C. sappan that has diverse biological activities, including neuroprotective, anti-inflammatory, antibacterial, and antioxidant properties. Brazilin inhibits Aβ (1-42) fibrillogenesis (IC50 = 1.5 μM) more potently than (-)-epigallocatechin gallate , cucurmin , and resveratrol (Item Nos. 10004235 | 70675). It also prevents remodeling of mature Aβ (1-42) fibrils. Brazilin inhibits the production of cytokines, including PGE2 and TNF-α (IC50s = 12.6 and 87.2 μM). It is effective against Gram-positive and Gram-negative bacteria with MICs ranging from 31.3 to 250 μg/ml. In addition, brazilin inhibits osteoclast differentiation mediated by RANKL and is protective against LPS-induced osteoporosis in mice at a dose of 100 mg/kg.
  • Uses Chiefly as a dye. Has also been recommended as indicator in acid-base titrations; acids = yellow, alkalies = carmine-red.
  • Uses inhibits platelet aggregation, PLA2, PKC, protein phosphatase, insulin receptor kinase, nitric oxide synthase, antineoplastic
  • Uses Brazilin is a hair dyeing composition that comprises a natural dye and fatty amine.
  • Definition ChEBI: A organic heterotetracyclic compound that is a red pigment obtained from the wood of Caesalpinia echinata (Brazil-wood) or Caesalpinia sappan (sappan-wood).
  • Purification Methods Brazilin crystallises from EtOH as yellow crystals which become orange when exposed to light and air, and is yellow in dilute acid but crimson in dilute alkali. When crystallised from H2O, it has m 247-248o. It forms coloured metal salts and is oxidized in air to Brazilein the quinonoid form. The (±)-form has been resolved, and the (+)-enantiomer has [] 20 +121o (c 1, MeOH). [Craig et al. J Org Chem 30 1573 1965,Morsingh & Robinson Tetrahedron 26 281 1970, Beilstein 17 H 194, 17 II 244, 17 III/IV 2711.]
BRAZILIN Preparation Products And Raw materials
Raw materials
Preparation Products
BRAZILIN Suppliers
Global(197)Suppliers
  • Supplier：
    Henan Tianfu Chemical Co.,Ltd.
  • Tel：+86-0371-55170693<br/>+86-19937530512
  • Email：info@tianfuchem.com
  • Country：China
  • ProdList：21628
  • Advantage：55
  • Supplier：
    Chongqing Chemdad Co., Ltd
  • Tel：+86-023-6139-8061<br/>+86-86-13650506873
  • Email：sales@chemdad.com
  • Country：China
  • ProdList：39894
  • Advantage：58
BRAZILIN Spectrum
474-07-7, BRAZILINRelated Search:
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  • BRAZILIN 巴西苏木素
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  • 474-07-7
  • Brazilin - Bio-X ?
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  • (6aS,11bR)-6,6a,7,11b-tetrahydroindeno[2,1-c]chromene-3,6a,9,10-tetraol
  • Brazilin, 98%, from Caesalpinia sappanL.
  • (+)-Brazilin
  • Brazilin >=98% (HPLC)
  • (6aS,11bR)-7,11b-Dihydrobenz[b]indeno[1,2-d]pyran-3,6a,9,10(6H)-tetrol
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  • Brazilin(6CI)
  • Benz[b]indeno[1,2-d]pyran-3,6a,9,10(6H)-tetrol,7,11b-dihydro-, (6aS,11bR)-
  • superbresiline
  • BRAZILIN
  • CI 75280
  • BRAZILIN (C.I. 75280)
  • pernambucoextract
  • limawoodextract
  • hypernicextract

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