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NEOMYCIN B

NEOMYCIN B Structure
NEOMYCIN B
  • CAS No.119-04-0
  • Chemical Name:NEOMYCIN B
  • CBNumber:CB8761428
  • Molecular Formula:C23H46N6O13
  • Formula Weight:614.64
  • MOL File:119-04-0.mol
NEOMYCIN B Property
  • Melting point >194°C (dec.)
  • Boiling point 658.4°C (rough estimate)
  • Density 1.3548 (rough estimate)
  • refractive index 1.6000 (estimate)
  • storage temp. 2-8°C
  • solubility Aqueous Acid (Slightly), Water (Slightly)
  • form liquid
  • pka 12.93±0.70(Predicted)
  • color clear
  • biological source Streptomyces fradiae
  • Merck 13,6482
  • Stability Hygroscopic
  • EWG's Food Scores 1
  • FDA UNII 4BOC774388
  • ATC code D09AA01,R01AX08,S01AA07
  • UNSPSC Code 12352207
  • NACRES NA.76
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H317-H334
  • Precautionary statements P261-P280-P284-P304+P340-P333+P313-P342+P311
NEOMYCIN B Price More Price(1)
  • Brand: Sigma-Aldrich(India)
  • Product number: N1142
  • Product name : Neomycin solution
  • Purity: with 10 mg/mL neomycin in 0.9% NaCl, 0.1 μm filtered, BioReagent, suitable for cell culture
  • Packaging: 20ML
  • Price: ₹1894.38
  • Updated: 2022/06/14
  • Buy: Buy

NEOMYCIN B Chemical Properties,Usage,Production

  • Uses Neomycin C is an aminoglycoside antibiotic found in many topical medications. Neomycin has been used as a preventive measure for hepatic encephalopathy and hypercholesterolemia.
  • Definition ChEBI: A tetracyclic antibacterial agent derived from neomycin, being a glycoside ester of neamine and neobiosamine B.
  • General Description Chemical structure: aminoglycoside
  • Biochem/physiol Actions Neomycin is an aminoglycoside antibiotic, produced by Streptomyces containing a minimum of 85% neomycin B. It acts as a selection agent for prokaryotic cells transformed using the neo selectable marker gene. Neomycin trisulfate is used to study the cytototoxic side effects of antibiotics, platelet-derived growth factor responses in certain fibroblasts and extraction of nuclear phosphatidylinositol 4,5-bisphosphate-interacting proteins. This product is recommended for use in cell culture applications at 5 mL/L.Mode of action: This product acts by binding to the 30S and 50S subunits, causing miscoding and inhibiting initiation and elongation during protein synthesis. Neomycin also blocks voltage-sensitive Ca2+ channels without affecting the Na+/Ca2+ antiporter in neurons.Antimicrobial spectrum: Neomycin acts against both gram-positive and gram-negative bacteria
  • IC 50 Aminoglycoside
NEOMYCIN B Preparation Products And Raw materials
Raw materials
Preparation Products
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NEOMYCIN B Spectrum
119-04-0, NEOMYCIN BRelated Search:
  • Interferes with Protein SynthesisSpectrum of Activity
  • Genetic Marker SelectionAntibiotics
  • Chemical Structure Class
  • Antineoplastic and Immunosuppressive AntibioticsAntibiotics
  • Antibiotics N-SAntibiotics
  • Antibiotics by Application
  • Antibiotics A to
  • Antibiotics
  • Antibacterial
  • AminoglycosidesAntibiotics
  • NA - NIMore...Close...
  • L - ZAlphabetic
  • N
  • Mechanism of Action
  • 原料药 API
  • Antibiotics N-S
  • Antibiotics
  • Antibiotics A to Z
  • BioChemical
  • 1190-04-0
  • 新霉素溶液 T1850 上海瑞楚
  • 新霉素溶液 T1779 上海瑞楚
  • 新生霉素溶液 T1481 上海瑞楚
  • 新生霉素溶液 T1462 上海瑞楚
  • 化合物 T15348
  • 新霉素B六乙酸酯
  • 新霉素标液
  • 硫酸弗兰西汀(新霉素B)
  • 新霉素B
  • 新霉素溶液
  • 119-04-0
  • Neomycin B/Neomycin B Acetate
  • Neomycin B Hexaacetate
  • FRADIOMYCIN B; NEOMYCIN B
  • NEOMYCIN B USP/EP/BP
  • D-Streptamine, O-2,6-diamino-2,6-dideoxy-β-L-idopyranosyl-(1→3)-O-β-D-ribofuranosyl-(1→5)-O-[2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-
  • Leo Red Dry Cow
  • Fraquinol
  • Francetin
  • Framycin
  • Framidal
  • Dekamycin III
  • Antibiotique EF 185
  • Antibiotic 10676
  • Neomycin solution
  • (2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4S,5R)-4-[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxyoxane-3,4-diol
  • (2R,3S,4R,5R,6R)-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-2-[(2S,3R,4S,5R)-4-[(2R,3R,4R,5S,6S)-6-(aminomethyl)-3-azanyl-4,5-dihydroxy-oxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-4,6-bis(azanyl)-3-hydroxy-cyclohexyl]oxy-5-azanyl-oxane-3,4-diol
  • 4-O-(2,6-Diamino-2,6-dideoxy-α-D-glucopyranosyl)-5-O-[3-O-(2,6-diamino-2,6-dideoxy-β-L-idopyranosyl)-β-D-ribofuranosyl]-2-deoxy-D-streptamine
  • soframycine
  • soframycin
  • framygen
  • framycetin
  • enterfram
  • antibiotique
  • actiline
  • actilin
  • NEOMYCIN B
  • NEOMYCIN STANDARD