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L(+)-Homoarginine hydrochloride

L(+)-Homoarginine hydrochloride Structure
L(+)-Homoarginine hydrochloride
  • CAS No.1483-01-8
  • Chemical Name:L(+)-Homoarginine hydrochloride
  • CBNumber:CB8732118
  • Molecular Formula:C7H17ClN4O2
  • Formula Weight:224.69
  • MOL File:1483-01-8.mol
L(+)-Homoarginine hydrochloride Property
  • Melting point 213-215 °C(lit.)
  • alpha 18 º (c=1, 1N HCl)
  • storage temp. Inert atmosphere,Room Temperature
  • solubility H2O: 50 mg/mL, clear to slightly hazy, faintly yellow
  • form Granular Powder
  • color White
  • Water Solubility Soluble in water(50 mg/mL).
  • BRN 4016621
  • Stability Moisture Sensitive
  • CAS DataBase Reference 1483-01-8(CAS DataBase Reference)
  • UNSPSC Code 12352209
  • NACRES NA.26
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302-H315-H319-H335
  • Precautionary statements P261-P305+P351+P338
L(+)-Homoarginine hydrochloride Price More Price(3)
  • Brand: Sigma-Aldrich(India)
  • Product number: H1007
  • Product name : L-Homoarginine hydrochloride
  • Purity: unnatural arginine analog
  • Packaging: 5G
  • Price: ₹31910
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: H1172
  • Product name : L-Homoarginine Hydrochloride
  • Purity: 
  • Packaging: 1G
  • Price: ₹3100
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: H1172
  • Product name : L-Homoarginine Hydrochloride
  • Purity: 
  • Packaging: 5G
  • Price: ₹10600
  • Updated: 2022/05/26
  • Buy: Buy

L(+)-Homoarginine hydrochloride Chemical Properties,Usage,Production

  • Description L-Homoarginine is an uncompetitive and organ-specific inhibitor of alkaline phosphatases. This non-essential amino acid inhibits human bone and liver alkaline phosphatases but has no effect on placental or intestinal isoenzymes. In vitro, L-homoarginine inhibits [3H]thymidine uptake by mouse myeloma MOPC 104E cells and inhibits proliferation of C3H/He mouse osteosarcoma cells. Pre-treatment with L-homoarginine delays in vivo tumor growth in a murine C3H/He osteosarcoma model. It also inhibits high-protein diet-induced pancreatic growth and enzyme secretion in bile-pancreatic juice-diverted rats, a model for the induction of pancreatic enzyme secretion with hypercholecystokininemia.
  • Chemical Properties White Powder
  • Uses An inhibitor of alkaline phosphatase isoenzymes. It is also an inhibitor of cellular transport of arginine by a sodium-independent high affinity y+ transporter. The substitution of homoarginine for arginine or lysine renders proteins resistant to proteolysis by trypsin. Arginine residues are often located at the active centers of proteins and enzymes. Replacing these arginines with homoarginine can elucidate protein function and structural requirements.
  • Uses An inhibitor of alkaline phosphatase isoenzymes. An analog of Homoarginine (H585000).
  • Biochem/physiol Actions Homoarginine is an inhibitor of tissue nonspecific alkaline phosphatase (TNALP). It is also an inhibitor of cellular transport of arginine by a sodium-independent high affinity y+ transporter.
  • IC 50 Human Endogenous Metabolite
L(+)-Homoarginine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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L(+)-Homoarginine hydrochloride Spectrum
1483-01-8, L(+)-Homoarginine hydrochlorideRelated Search:
  • Amino Acids 13C, 2H, 15N
  • Homoarginine [HomoArg]
  • Nitric Oxide Reagents
  • Amino Acids & Derivatives
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Inhibitors
  • Aliphatics
  • 医用原料
  • 抑制剂
  • 通用生化试剂-氨基酸
  • 生化试剂-氨基酸类
  • 中药对照品
  • 化学试剂
  • 非天然氨基酸
  • 保护氨基酸
  • 医药中间体
  • 其他生化试剂
  • 氨基酸,多肽
  • 氨基酸类
  • 非天然氨基酸极其衍生物
  • 生化试剂
  • 中间体
  • 氨基酸及其衍生物
  • 氨基酸
  • Specialty Synthesis
  • Peptide Synthesis
  • Unnatural Amino Acid Derivatives
  • Homo-Amino Acids
  • The substitution of homoarginine for arginine or lysine renders proteins resistant to proteolysis by trypsin. Arginine residues are often located at the active centers of proteins and enzymes.
  • C7H17ClN4O2
  • H2NCNHNHCH24NH2CO2HHCl
  • C7H16N4O2xHCl
  • C7H16N4O2ClH
  • C7H16N4O2HCl
  • H2NCNHNHCH24CHNH2CO2HHCl
  • L-高精氨酸:盐酸盐(13C7,98%+
  • (S)-2-氨基-6-胍基己酸盐酸盐
  • -高精氨酸盐酸盐
  • L-高精氨酸甲酯.2盐酸盐
  • L-高精氨酸
  • L-高精氨酸 盐酸盐,98+%
  • 高精氨酸盐酸盐
  • L-高精氨酸HCL
  • L-高精氨酸盐酸盐
  • 1483-01-8
  • <sc>L</sc>-Homoarginine hydrochloride
  • L-Homoarginine Hydrochloride, ≥ 97.0%
  • L(+)-Homoarginine hydrochloride USP/EP/BP
  • -(+)-Homoarginine hydrochL
  • inine hydrochL
  • -(+)-Homoarg
  • NSC 145416
  • L-HomoarginineHydrochloride&gt
  • (2S)-2-ammonio-6-(diaminomethylideneammonio)hexanoate
  • L-Lysine,N6-(aminoiminomethyl)-, hydrochloride (1:1)
  • L-Homoarg.hcl
  • L(+)-Homoarginine hy