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L-Arginine hydrochloride

CAS No.1119-34-2
Chemical Name:L-Arginine hydrochloride
CBNumber:CB9700536
Molecular Formula:C6H15ClN4O2
Formula Weight:210.66
MOL File:1119-34-2.mol

L-Arginine hydrochloride Property

Melting point 226-230 °C(lit.)
Boiling point 235℃[at 101 325 Pa]
alpha 22 º (c=8,6N HCl)
Density 1.42
bulk density 1250kg/m3
vapor pressure <1 Pa (20 °C)
FEMA 3819 | L-ARGININE
storage temp. 2-8°C
solubility H₂O: 100 mg/mL
form powder
pka 1[at 20 ℃]
color white
PH 5.5-7.0 (25℃, 1M in H2O)
Odor odorless
PH Range 5.5 - 7
optical activity [α]20/D +22.0±0.5°, c = 5% in 5 M HCl
biological source non-animal source
Water Solubility Soluble in water. Slightly soluble in hot alcohol.
Sensitive Hygroscopic
λmax λ: 260 nm Amax: ≤0.2
λ: 280 nm Amax: ≤0.1
Merck 14,780
BRN 3631658
Stability Stable. Incompatible with strong oxidizing agents.
LogP -8.5--3.24 at 25℃
CAS DataBase Reference 1119-34-2(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII F7LTH1E20Y
NCI Drug Dictionary arginine hydrochloride
ATC code B05XB01
EPA Substance Registry System L-Arginine, monohydrochloride (1119-34-2)
UNSPSC Code 85151701
NACRES NA.26

Safety

Hazard Codes :Xi,Xn
Risk Statements :37-36/38-36/37/38-20/21/22
Safety Statements :37/39-26-24/25-36
WGK Germany :2
RTECS :CF1995500
F :3-10
TSCA :Yes
HS Code :29252000
Toxicity :LD50 orally in Rabbit: 12000 mg/kg

NFPA 704:

	0
1		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordWarning
Hazard statements H315-H319
Precautionary statements P305+P351+P338

L-Arginine hydrochloride Price More Price(24)

Brand: Sigma-Aldrich(India)
Product number: A5131
Product name : L-Arginine monohydrochloride
Purity: reagent grade, ≥98% (HPLC), powder
Packaging: 10G
Price: ₹2045.93
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: A6969
Product name : L-Arginine monohydrochloride
Purity: not synthetic, meets EP, JP, USP testing specifications, suitable for cell culture, 98.5-101.0%
Packaging: 25G
Price: ₹2749.55
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: A6969
Product name : L-Arginine monohydrochloride
Purity: not synthetic, meets EP, JP, USP testing specifications, suitable for cell culture, 98.5-101.0%
Packaging: 100G
Price: ₹7404.3
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: A5131
Product name : L-Arginine monohydrochloride
Purity: reagent grade, ≥98% (HPLC), powder
Packaging: 100G
Price: ₹2186.65
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: A5131
Product name : L-Arginine monohydrochloride
Purity: reagent grade, ≥98% (HPLC), powder
Packaging: 25G
Price: ₹2403.15
Updated: 2022/06/14
Buy: Buy

L-Arginine hydrochloride Chemical Properties,Usage,Production

Description L-Arginine hydrochloride is a salt form of L-Arginine, where hydrochloric acid is added to enhance stability and solubility. Arginine hydrochloride is a L-alpha-amino acid. An essential amino acid that is physiologically active in the L-form. L-Arginine might be effective at lowering blood pressure, reducing the symptoms of angina and PAD , and treating erectile dysfunction due to a physical cause.
Chemical Properties White crystalline powder
Uses gastric acid depressant
Uses L-Arginine monohydrochloride is used in the treatment of heart and circulatory diseases. It is a precursor of nitric oxide synthesis that induces vasodilation in vivo, there by relaxing blood vessels. It is also used in the treatment of angina and other cardiovascular problems. It is an important intermediate in the urea cycle and involved in the detoxification of nitrogenous wastes. It is commonly used in cell culture media and drug development.
Uses An essential amino acid for human development. Precursor for nitric oxide. Ammonia detoxicant (hepatic failure); diagnostic aid (pituitary function).
Definition ChEBI: Arginine hydrochloride is a L-alpha-amino acid.
brand name R-Gene 10 (Pharmacia & Upjohn).
Biochem/physiol Actions L-Arginine is considered as a semi essential amino acid. In most mammals including humans, L-Arginine synthesis occurs through intestinal-renal axis, from glutamine, glutamate and proline. Abnormal levels of L-Arginine is associated with the development of kidney and cardiovascular disease. L-arginine is found to decrease fat mass and visceral adiposity.
Side effects L-arginine has some potential side effects to consider when taking it as a supplement. Some of the more common and benign side effects can include: nausea, diarrhea, bloating, and abdominal pain. However, L-arginine may result in some serious complications.
Safety Profile Moderately toxic by intraperitoneal route. Mildly toxic by ingestion. An experimental teratogen. When heated to decomposition it emits very toxic fumes of NOx and HCl.
Purification Methods A likely impurity is ornithine. Crystallise the salt from H2O at pH 5-7, by adding EtOH to 80% (v/v). [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 p 1841 1961, Beilstein 4 IV 2649.]