ChemicalBook > CAS DataBase List > 3,5-DIHYDROXY-7-METHOXY-2-(4-METHOXY-PHENYL)-CHROMEN-4-ONE

3,5-DIHYDROXY-7-METHOXY-2-(4-METHOXY-PHENYL)-CHROMEN-4-ONE

3,5-DIHYDROXY-7-METHOXY-2-(4-METHOXY-PHENYL)-CHROMEN-4-ONE Structure
3,5-DIHYDROXY-7-METHOXY-2-(4-METHOXY-PHENYL)-CHROMEN-4-ONE
  • CAS No.15486-33-6
  • Chemical Name:3,5-DIHYDROXY-7-METHOXY-2-(4-METHOXY-PHENYL)-CHROMEN-4-ONE
  • CBNumber:CB8459237
  • Molecular Formula:C17H14O6
  • Formula Weight:314.29
  • MOL File:15486-33-6.mol
3,5-DIHYDROXY-7-METHOXY-2-(4-METHOXY-PHENYL)-CHROMEN-4-ONE Property
  • storage temp. 2-8°C
  • form Solid
  • color Light yellow to yellow
  • LogP 3.247 (est)
  • FDA UNII Y4D3RA49HD
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

3,5-DIHYDROXY-7-METHOXY-2-(4-METHOXY-PHENYL)-CHROMEN-4-ONE Chemical Properties,Usage,Production

  • Uses Kaempferol-7,4'-dimethyl ether is a PTP1B inhibitor, and also can inhibit the production of NO. Kaempferol-7,4'-dimethyl ether shows the inhibition rate of 46.1% at 100 μM. Kaempferol-7,4'-dimethyl ether inhibits PTP1B activity with IC50 value of 16.92 μM[1][2].
  • Definition ChEBI: 7,4'-dimethylkaempferol is a dimethoxyflavone that is kaempferol in which the hydroxy groups at position 4' and 7 have been replaced by methoxy groups. It is a component of bee glue and has been isolated from several plant species including Betula exilis, Zingiber mekongense and Alpinia flabellata. It has a role as an antioxidant and a plant metabolite. It is a dimethoxyflavone, a dihydroxyflavone and a member of flavonols. It is functionally related to a kaempferol. It is a conjugate acid of a 7,4'-O-dimethylkaempferol 3-olate.
  • References [1] Teeratad, et al. Inhibition of nitric oxide production by compounds from Boesenbergia longiflora using lipopolysaccharide-stimulated RAW264.7 macrophage cells.[J]. Songklanakarin Journal of Science & Technology, 2013.
    [2] To D-C, et al. PTP1B Inhibitory Flavonoids From Orthosiphon stamineus Benth. and Their Growth Inhibition on Human Breast Cancer Cells. Natural Product Communications. 2020,15(1).
3,5-DIHYDROXY-7-METHOXY-2-(4-METHOXY-PHENYL)-CHROMEN-4-ONE Preparation Products And Raw materials
Raw materials
Preparation Products
3,5-DIHYDROXY-7-METHOXY-2-(4-METHOXY-PHENYL)-CHROMEN-4-ONE Suppliers
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3,5-DIHYDROXY-7-METHOXY-2-(4-METHOXY-PHENYL)-CHROMEN-4-ONE Spectrum
15486-33-6, 3,5-DIHYDROXY-7-METHOXY-2-(4-METHOXY-PHENYL)-CHROMEN-4-ONERelated Search:
  • Flavanols
  • 黄酮类
  • 抑制剂
  • 黄酮
  • 植物提取物
  • 标准品
  • 山奈酚-4',7-二甲醚
  • 3,5-二羟基-7-甲氧基-2-(4-甲氧基苯基)-4H-苯并吡喃-4-酮
  • 山奈酚-7,4'-二甲醚
  • 山柰酚-7,4'-二甲醚
  • 3,5-二烃基-4,7-二甲氧基黄酮
  • 3,5-二羟基-7-甲氧基-2-(4-甲氧基苯基)-色烯-4-酮
  • 3,5-二羟基-4',7-二甲氧基黄酮
  • 15486-33-6
  • Kaempferol-7,4''-dimethyl ether
  • Kaempferol-4',7-dimethylether
  • 7-O-Dimethylkaempferol
  • Kaempferol 7,4'-dimethyl ether
  • 3,5-Dihydroxy-4',7-dimethoxyflavone
  • 5-Dihydroxy-4'
  • 4H-1-Benzopyran-4-one, 3,5-dihydroxy-7-methoxy-2-(4-methoxyphenyl)-
  • 7-dimethoxyflavone
  • 3,5-DIHYDROXY-4',7-DIMETHOXYFLAV
  • 3,5-Dihydroxy-7-Methoxy-2-(4-Methoxyphenyl)-4H-chroMen-4-one
  • Einecs 239-513-1
  • Kaempferol 4',7-dimethyl ether
  • 4'-O,7-O-Dimethylkaempferol
  • 2-(4-Methoxyphenyl)-3,5-dihydroxy-7-methoxy-4H-1-benzopyran-4-one
  • 3,5-Dihydroxy-7-methoxy-2-(4-methoxy-phenyl)-
  • 3,5-dihydroxy-7-methoxy-2-(4-methoxyphenyl)-4-benzopyrone
  • 3,5-DIHYDROXY-7-METHOXY-2-(4-METHOXY-PHENYL)-CHROMEN-4-ONE
  • 3,5-DIHYDROXY-7,4'-DIMETHOXYFLAVONE
  • KAEMPFEROL-7,4'-DIMETHYL ETHER

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